Perinatal Transmission of Human Papillomavirus in Infants: Relationship Between Infection Rate and Mode of Delivery
OBJECTIVETo determine the transmission rate of human papillomavirus (HPV) in newborn infants of HPV-positive women and to assess the relationship between perinatal HPV transmission and mode of delivery. METHODSThree hundred one pregnant women were selectedvaginal delivery (n = 160) or cesarean deliv...
Gespeichert in:
| Veröffentlicht in: | Obstetrics and gynecology (New York. 1953) 1998-01, Vol.91 (1), p.92-96 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 96 |
|---|---|
| container_issue | 1 |
| container_start_page | 92 |
| container_title | Obstetrics and gynecology (New York. 1953) |
| container_volume | 91 |
| creator | TSENG, CHIH-JEN LIANG, CHING-CHUNG SOONG, YUNG-KUEI PAO, CHIA-C |
| description | OBJECTIVETo determine the transmission rate of human papillomavirus (HPV) in newborn infants of HPV-positive women and to assess the relationship between perinatal HPV transmission and mode of delivery.
METHODSThree hundred one pregnant women were selectedvaginal delivery (n = 160) or cesarean delivery (n = 141). We assessed the presence of the HPV types 16 and 18 DNA sequences in buccal and genital swabs of neonates born to HPV-positive mothers, using the polymerase chain reaction.
RESULTSThe overall frequency of HPV 16/18 infection among the pregnant women was 22.6% (68/301). At birth, the overall frequency of HPV transmission from HPV 16/18-positive mothers to newborns was 39.7% (27/68). A significantly higher rate of HPV 16/18 infection was found at birth when infants were delivered vaginally than when infants were delivered by cesarean (18/35 or 51.4% versus 9/33 or 27.3%, P = .042). However, there was no significant difference in the incidence of perinatal HPV infection between the HPV types 16 and 18 in either vaginal delivery group or in the cesarean delivery group (all P >.100). No significant difference was found between the buccal and genital sites (27/68 versus 21/68, P = .234) or between male and female infants overall (12/36 versus 15/32, P = .255).
CONCLUSIONThe findings suggest that neonates are at higher risk for exposure to HPV after vaginal delivery than after cesarean delivery. |
| doi_str_mv | 10.1016/s0029-7844(97)00593-0 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_79683062</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>79683062</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4968-55eab5b6b64e0ad1559bf05f5ef35467bcd642be152917d8592d39013276f1be3</originalsourceid><addsrcrecordid>eNo9kc1u3CAUhVHVKJ2mfYRILKqqXTi5gAHTXZr-JFKiRmkqdYewfa2hxfYU7Izy9sWZ0awQnO_cAwdCThmcMWDqPAFwU-iqLD8Y_RFAGlHAC7JilRYFF-L3S7I6IK_I65T-AGSjEcfk2JSq1LxakXSH0Q9ucoE-RDek3qfkx4GOHb2aezfQO7fxIYy9e_RxTtQP9Hro3DClT_Qeg5synNZ-Qz_jtEV8VrFZTum9m5C6oaW3Y4vLwC8Y_CPGpzfkqHMh4dv9ekJ-ffv6cHlV3Pz4fn15cVM0pVFVISW6WtaqViWCa5mUpu5AdhI7IUul66ZVJa-RSW6YbitpeCsMMMG16liN4oS8383dxPHfjGmy-XUNhuAGHOdkdU4RoHgG5Q5s4phSxM5uou9dfLIM7FK2_bk0aZcmrdH2uWwL2Xe6D5jrHtuDa99u1t_tdZcaF7pccOPTAeNgtFI6Y-UO245hwpj-hnmL0a7RhWmdwyDfUULBjKmA5V2x_GMl_gNle5fn</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>79683062</pqid></control><display><type>article</type><title>Perinatal Transmission of Human Papillomavirus in Infants: Relationship Between Infection Rate and Mode of Delivery</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><creator>TSENG, CHIH-JEN ; LIANG, CHING-CHUNG ; SOONG, YUNG-KUEI ; PAO, CHIA-C</creator><creatorcontrib>TSENG, CHIH-JEN ; LIANG, CHING-CHUNG ; SOONG, YUNG-KUEI ; PAO, CHIA-C</creatorcontrib><description>OBJECTIVETo determine the transmission rate of human papillomavirus (HPV) in newborn infants of HPV-positive women and to assess the relationship between perinatal HPV transmission and mode of delivery.
METHODSThree hundred one pregnant women were selectedvaginal delivery (n = 160) or cesarean delivery (n = 141). We assessed the presence of the HPV types 16 and 18 DNA sequences in buccal and genital swabs of neonates born to HPV-positive mothers, using the polymerase chain reaction.
RESULTSThe overall frequency of HPV 16/18 infection among the pregnant women was 22.6% (68/301). At birth, the overall frequency of HPV transmission from HPV 16/18-positive mothers to newborns was 39.7% (27/68). A significantly higher rate of HPV 16/18 infection was found at birth when infants were delivered vaginally than when infants were delivered by cesarean (18/35 or 51.4% versus 9/33 or 27.3%, P = .042). However, there was no significant difference in the incidence of perinatal HPV infection between the HPV types 16 and 18 in either vaginal delivery group or in the cesarean delivery group (all P >.100). No significant difference was found between the buccal and genital sites (27/68 versus 21/68, P = .234) or between male and female infants overall (12/36 versus 15/32, P = .255).
CONCLUSIONThe findings suggest that neonates are at higher risk for exposure to HPV after vaginal delivery than after cesarean delivery.</description><identifier>ISSN: 0029-7844</identifier><identifier>EISSN: 1873-233X</identifier><identifier>DOI: 10.1016/s0029-7844(97)00593-0</identifier><identifier>PMID: 9464728</identifier><identifier>CODEN: OBGNAS</identifier><language>eng</language><publisher>New York, NY: The American College of Obstetricians and Gynecologists</publisher><subject>Adolescent ; Adult ; Base Sequence ; Biological and medical sciences ; Cervix Uteri - pathology ; Delivery, Obstetric - adverse effects ; Delivery, Obstetric - methods ; DNA - genetics ; DNA Primers - chemistry ; Female ; Human viral diseases ; Humans ; Infant, Newborn ; Infectious Disease Transmission, Vertical - statistics & numerical data ; Infectious diseases ; Male ; Medical sciences ; Papillomaviridae - genetics ; Papillomaviridae - pathogenicity ; Papillomavirus Infections - epidemiology ; Papillomavirus Infections - transmission ; Papillomavirus Infections - virology ; Polymerase Chain Reaction ; Pregnancy ; Pregnancy Complications, Infectious - epidemiology ; Pregnancy Complications, Infectious - virology ; Tumor Virus Infections - epidemiology ; Tumor Virus Infections - transmission ; Tumor Virus Infections - virology ; Vaginal Smears ; Viral diseases ; Viral diseases of the genital and urinary system</subject><ispartof>Obstetrics and gynecology (New York. 1953), 1998-01, Vol.91 (1), p.92-96</ispartof><rights>1998 The American College of Obstetricians and Gynecologists</rights><rights>1998 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4968-55eab5b6b64e0ad1559bf05f5ef35467bcd642be152917d8592d39013276f1be3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4023,27922,27923,27924</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2097667$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9464728$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>TSENG, CHIH-JEN</creatorcontrib><creatorcontrib>LIANG, CHING-CHUNG</creatorcontrib><creatorcontrib>SOONG, YUNG-KUEI</creatorcontrib><creatorcontrib>PAO, CHIA-C</creatorcontrib><title>Perinatal Transmission of Human Papillomavirus in Infants: Relationship Between Infection Rate and Mode of Delivery</title><title>Obstetrics and gynecology (New York. 1953)</title><addtitle>Obstet Gynecol</addtitle><description>OBJECTIVETo determine the transmission rate of human papillomavirus (HPV) in newborn infants of HPV-positive women and to assess the relationship between perinatal HPV transmission and mode of delivery.
METHODSThree hundred one pregnant women were selectedvaginal delivery (n = 160) or cesarean delivery (n = 141). We assessed the presence of the HPV types 16 and 18 DNA sequences in buccal and genital swabs of neonates born to HPV-positive mothers, using the polymerase chain reaction.
RESULTSThe overall frequency of HPV 16/18 infection among the pregnant women was 22.6% (68/301). At birth, the overall frequency of HPV transmission from HPV 16/18-positive mothers to newborns was 39.7% (27/68). A significantly higher rate of HPV 16/18 infection was found at birth when infants were delivered vaginally than when infants were delivered by cesarean (18/35 or 51.4% versus 9/33 or 27.3%, P = .042). However, there was no significant difference in the incidence of perinatal HPV infection between the HPV types 16 and 18 in either vaginal delivery group or in the cesarean delivery group (all P >.100). No significant difference was found between the buccal and genital sites (27/68 versus 21/68, P = .234) or between male and female infants overall (12/36 versus 15/32, P = .255).
CONCLUSIONThe findings suggest that neonates are at higher risk for exposure to HPV after vaginal delivery than after cesarean delivery.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Base Sequence</subject><subject>Biological and medical sciences</subject><subject>Cervix Uteri - pathology</subject><subject>Delivery, Obstetric - adverse effects</subject><subject>Delivery, Obstetric - methods</subject><subject>DNA - genetics</subject><subject>DNA Primers - chemistry</subject><subject>Female</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Infectious Disease Transmission, Vertical - statistics & numerical data</subject><subject>Infectious diseases</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Papillomaviridae - genetics</subject><subject>Papillomaviridae - pathogenicity</subject><subject>Papillomavirus Infections - epidemiology</subject><subject>Papillomavirus Infections - transmission</subject><subject>Papillomavirus Infections - virology</subject><subject>Polymerase Chain Reaction</subject><subject>Pregnancy</subject><subject>Pregnancy Complications, Infectious - epidemiology</subject><subject>Pregnancy Complications, Infectious - virology</subject><subject>Tumor Virus Infections - epidemiology</subject><subject>Tumor Virus Infections - transmission</subject><subject>Tumor Virus Infections - virology</subject><subject>Vaginal Smears</subject><subject>Viral diseases</subject><subject>Viral diseases of the genital and urinary system</subject><issn>0029-7844</issn><issn>1873-233X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kc1u3CAUhVHVKJ2mfYRILKqqXTi5gAHTXZr-JFKiRmkqdYewfa2hxfYU7Izy9sWZ0awQnO_cAwdCThmcMWDqPAFwU-iqLD8Y_RFAGlHAC7JilRYFF-L3S7I6IK_I65T-AGSjEcfk2JSq1LxakXSH0Q9ucoE-RDek3qfkx4GOHb2aezfQO7fxIYy9e_RxTtQP9Hro3DClT_Qeg5synNZ-Qz_jtEV8VrFZTum9m5C6oaW3Y4vLwC8Y_CPGpzfkqHMh4dv9ekJ-ffv6cHlV3Pz4fn15cVM0pVFVISW6WtaqViWCa5mUpu5AdhI7IUul66ZVJa-RSW6YbitpeCsMMMG16liN4oS8383dxPHfjGmy-XUNhuAGHOdkdU4RoHgG5Q5s4phSxM5uou9dfLIM7FK2_bk0aZcmrdH2uWwL2Xe6D5jrHtuDa99u1t_tdZcaF7pccOPTAeNgtFI6Y-UO245hwpj-hnmL0a7RhWmdwyDfUULBjKmA5V2x_GMl_gNle5fn</recordid><startdate>199801</startdate><enddate>199801</enddate><creator>TSENG, CHIH-JEN</creator><creator>LIANG, CHING-CHUNG</creator><creator>SOONG, YUNG-KUEI</creator><creator>PAO, CHIA-C</creator><general>The American College of Obstetricians and Gynecologists</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199801</creationdate><title>Perinatal Transmission of Human Papillomavirus in Infants: Relationship Between Infection Rate and Mode of Delivery</title><author>TSENG, CHIH-JEN ; LIANG, CHING-CHUNG ; SOONG, YUNG-KUEI ; PAO, CHIA-C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4968-55eab5b6b64e0ad1559bf05f5ef35467bcd642be152917d8592d39013276f1be3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Base Sequence</topic><topic>Biological and medical sciences</topic><topic>Cervix Uteri - pathology</topic><topic>Delivery, Obstetric - adverse effects</topic><topic>Delivery, Obstetric - methods</topic><topic>DNA - genetics</topic><topic>DNA Primers - chemistry</topic><topic>Female</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Infectious Disease Transmission, Vertical - statistics & numerical data</topic><topic>Infectious diseases</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Papillomaviridae - genetics</topic><topic>Papillomaviridae - pathogenicity</topic><topic>Papillomavirus Infections - epidemiology</topic><topic>Papillomavirus Infections - transmission</topic><topic>Papillomavirus Infections - virology</topic><topic>Polymerase Chain Reaction</topic><topic>Pregnancy</topic><topic>Pregnancy Complications, Infectious - epidemiology</topic><topic>Pregnancy Complications, Infectious - virology</topic><topic>Tumor Virus Infections - epidemiology</topic><topic>Tumor Virus Infections - transmission</topic><topic>Tumor Virus Infections - virology</topic><topic>Vaginal Smears</topic><topic>Viral diseases</topic><topic>Viral diseases of the genital and urinary system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>TSENG, CHIH-JEN</creatorcontrib><creatorcontrib>LIANG, CHING-CHUNG</creatorcontrib><creatorcontrib>SOONG, YUNG-KUEI</creatorcontrib><creatorcontrib>PAO, CHIA-C</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>TSENG, CHIH-JEN</au><au>LIANG, CHING-CHUNG</au><au>SOONG, YUNG-KUEI</au><au>PAO, CHIA-C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Perinatal Transmission of Human Papillomavirus in Infants: Relationship Between Infection Rate and Mode of Delivery</atitle><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle><addtitle>Obstet Gynecol</addtitle><date>1998-01</date><risdate>1998</risdate><volume>91</volume><issue>1</issue><spage>92</spage><epage>96</epage><pages>92-96</pages><issn>0029-7844</issn><eissn>1873-233X</eissn><coden>OBGNAS</coden><abstract>OBJECTIVETo determine the transmission rate of human papillomavirus (HPV) in newborn infants of HPV-positive women and to assess the relationship between perinatal HPV transmission and mode of delivery.
METHODSThree hundred one pregnant women were selectedvaginal delivery (n = 160) or cesarean delivery (n = 141). We assessed the presence of the HPV types 16 and 18 DNA sequences in buccal and genital swabs of neonates born to HPV-positive mothers, using the polymerase chain reaction.
RESULTSThe overall frequency of HPV 16/18 infection among the pregnant women was 22.6% (68/301). At birth, the overall frequency of HPV transmission from HPV 16/18-positive mothers to newborns was 39.7% (27/68). A significantly higher rate of HPV 16/18 infection was found at birth when infants were delivered vaginally than when infants were delivered by cesarean (18/35 or 51.4% versus 9/33 or 27.3%, P = .042). However, there was no significant difference in the incidence of perinatal HPV infection between the HPV types 16 and 18 in either vaginal delivery group or in the cesarean delivery group (all P >.100). No significant difference was found between the buccal and genital sites (27/68 versus 21/68, P = .234) or between male and female infants overall (12/36 versus 15/32, P = .255).
CONCLUSIONThe findings suggest that neonates are at higher risk for exposure to HPV after vaginal delivery than after cesarean delivery.</abstract><cop>New York, NY</cop><pub>The American College of Obstetricians and Gynecologists</pub><pmid>9464728</pmid><doi>10.1016/s0029-7844(97)00593-0</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0029-7844 |
| ispartof | Obstetrics and gynecology (New York. 1953), 1998-01, Vol.91 (1), p.92-96 |
| issn | 0029-7844 1873-233X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_79683062 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adolescent Adult Base Sequence Biological and medical sciences Cervix Uteri - pathology Delivery, Obstetric - adverse effects Delivery, Obstetric - methods DNA - genetics DNA Primers - chemistry Female Human viral diseases Humans Infant, Newborn Infectious Disease Transmission, Vertical - statistics & numerical data Infectious diseases Male Medical sciences Papillomaviridae - genetics Papillomaviridae - pathogenicity Papillomavirus Infections - epidemiology Papillomavirus Infections - transmission Papillomavirus Infections - virology Polymerase Chain Reaction Pregnancy Pregnancy Complications, Infectious - epidemiology Pregnancy Complications, Infectious - virology Tumor Virus Infections - epidemiology Tumor Virus Infections - transmission Tumor Virus Infections - virology Vaginal Smears Viral diseases Viral diseases of the genital and urinary system |
| title | Perinatal Transmission of Human Papillomavirus in Infants: Relationship Between Infection Rate and Mode of Delivery |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T06%3A37%3A42IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Perinatal%20Transmission%20of%20Human%20Papillomavirus%20in%20Infants:%20Relationship%20Between%20Infection%20Rate%20and%20Mode%20of%20Delivery&rft.jtitle=Obstetrics%20and%20gynecology%20(New%20York.%201953)&rft.au=TSENG,%20CHIH-JEN&rft.date=1998-01&rft.volume=91&rft.issue=1&rft.spage=92&rft.epage=96&rft.pages=92-96&rft.issn=0029-7844&rft.eissn=1873-233X&rft.coden=OBGNAS&rft_id=info:doi/10.1016/s0029-7844(97)00593-0&rft_dat=%3Cproquest_cross%3E79683062%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=79683062&rft_id=info:pmid/9464728&rfr_iscdi=true |