A Furanoid Labdane Diterpene from Potamogeton nodosus
A new furanoid diterpene, 15,16-epoxy-12-oxo-8(17),13(16),14-labdatrien-20,19-olide (1) was isolated from an ethanolic extract of Potamogeton nodosus. Its structure was elucidated by the usual spectroscopic methods, including 2D NMR techniques. Compound 1 was found to exhibit moderate inhibitory act...
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Veröffentlicht in: | Journal of natural products (Washington, D.C.) D.C.), 1998-01, Vol.61 (1), p.156-157 |
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container_title | Journal of natural products (Washington, D.C.) |
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creator | Qais, Nazmul Mandal, Mushfiqur Rahman Rashid, Mohammad Abdur Jabbar, Abdul Koshino, Hiroyuki Nagasawa, Kazuo Nakata, Tadashi |
description | A new furanoid diterpene, 15,16-epoxy-12-oxo-8(17),13(16),14-labdatrien-20,19-olide (1) was isolated from an ethanolic extract of Potamogeton nodosus. Its structure was elucidated by the usual spectroscopic methods, including 2D NMR techniques. Compound 1 was found to exhibit moderate inhibitory activity against a number of both Gram-positive and Gram-negative bacteria. |
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Its structure was elucidated by the usual spectroscopic methods, including 2D NMR techniques. Compound 1 was found to exhibit moderate inhibitory activity against a number of both Gram-positive and Gram-negative bacteria.</description><identifier>ISSN: 0163-3864</identifier><identifier>EISSN: 1520-6025</identifier><identifier>DOI: 10.1021/np9702244</identifier><identifier>PMID: 9461667</identifier><identifier>CODEN: JNPRDF</identifier><language>eng</language><publisher>Washington, DC: American Chemical Society</publisher><subject>Anti-Bacterial Agents - isolation & purification ; Anti-Bacterial Agents - pharmacology ; AQUATIC PLANTS ; BACTERICIDAS ; BACTERICIDE ; BACTERICIDES ; BANGLADESH ; Biological and medical sciences ; CHEMICAL COMPOSITION ; CHEMICAL STRUCTURE ; COMPOSICION QUIMICA ; COMPOSITION CHIMIQUE ; DITERPENOIDE ; DITERPENOIDS ; DITERPENOS ; DRUG PLANTS ; ESPECTROMETRIA ; ESTRUCTURA QUIMICA ; General pharmacology ; Gram-Negative Bacteria - drug effects ; Gram-Positive Bacteria - drug effects ; India ; Magnetic Resonance Spectroscopy ; Medical sciences ; Microbial Sensitivity Tests ; Pharmacognosy. 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Drug treatments ; PLANTAS ACUATICAS ; PLANTAS MEDICINALES ; PLANTE AQUATIQUE ; PLANTE MEDICINALE ; Plants, Medicinal - chemistry ; POTAMOGETON ; RACINE ; RAICES ; ROOTS ; SPECTRAL ANALYSIS ; SPECTROMETRIE ; SPECTROMETRY ; STRUCTURE CHIMIQUE</subject><ispartof>Journal of natural products (Washington, D.C.), 1998-01, Vol.61 (1), p.156-157</ispartof><rights>Copyright © 1998 American Chemical Society and American Society of Pharmacognosy</rights><rights>1998 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a399t-3b0f549d8a6c47dea7a82f1773a7cab54865072c1354159b24a935f7761b8cdb3</citedby><cites>FETCH-LOGICAL-a399t-3b0f549d8a6c47dea7a82f1773a7cab54865072c1354159b24a935f7761b8cdb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/np9702244$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/np9702244$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>314,780,784,2765,27076,27924,27925,56738,56788</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2146103$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9461667$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Qais, Nazmul</creatorcontrib><creatorcontrib>Mandal, Mushfiqur Rahman</creatorcontrib><creatorcontrib>Rashid, Mohammad Abdur</creatorcontrib><creatorcontrib>Jabbar, Abdul</creatorcontrib><creatorcontrib>Koshino, Hiroyuki</creatorcontrib><creatorcontrib>Nagasawa, Kazuo</creatorcontrib><creatorcontrib>Nakata, Tadashi</creatorcontrib><title>A Furanoid Labdane Diterpene from Potamogeton nodosus</title><title>Journal of natural products (Washington, D.C.)</title><addtitle>J. Nat. Prod</addtitle><description>A new furanoid diterpene, 15,16-epoxy-12-oxo-8(17),13(16),14-labdatrien-20,19-olide (1) was isolated from an ethanolic extract of Potamogeton nodosus. Its structure was elucidated by the usual spectroscopic methods, including 2D NMR techniques. Compound 1 was found to exhibit moderate inhibitory activity against a number of both Gram-positive and Gram-negative bacteria.</description><subject>Anti-Bacterial Agents - isolation & purification</subject><subject>Anti-Bacterial Agents - pharmacology</subject><subject>AQUATIC PLANTS</subject><subject>BACTERICIDAS</subject><subject>BACTERICIDE</subject><subject>BACTERICIDES</subject><subject>BANGLADESH</subject><subject>Biological and medical sciences</subject><subject>CHEMICAL COMPOSITION</subject><subject>CHEMICAL STRUCTURE</subject><subject>COMPOSICION QUIMICA</subject><subject>COMPOSITION CHIMIQUE</subject><subject>DITERPENOIDE</subject><subject>DITERPENOIDS</subject><subject>DITERPENOS</subject><subject>DRUG PLANTS</subject><subject>ESPECTROMETRIA</subject><subject>ESTRUCTURA QUIMICA</subject><subject>General pharmacology</subject><subject>Gram-Negative Bacteria - drug effects</subject><subject>Gram-Positive Bacteria - drug effects</subject><subject>India</subject><subject>Magnetic Resonance Spectroscopy</subject><subject>Medical sciences</subject><subject>Microbial Sensitivity Tests</subject><subject>Pharmacognosy. Homeopathy. Health food</subject><subject>Pharmacology. Drug treatments</subject><subject>PLANTAS ACUATICAS</subject><subject>PLANTAS MEDICINALES</subject><subject>PLANTE AQUATIQUE</subject><subject>PLANTE MEDICINALE</subject><subject>Plants, Medicinal - chemistry</subject><subject>POTAMOGETON</subject><subject>RACINE</subject><subject>RAICES</subject><subject>ROOTS</subject><subject>SPECTRAL ANALYSIS</subject><subject>SPECTROMETRIE</subject><subject>SPECTROMETRY</subject><subject>STRUCTURE CHIMIQUE</subject><issn>0163-3864</issn><issn>1520-6025</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkEtLxDAUhYMoOj4W_gChCxVcVPNOsxx8Q8GBGdfhNk2lOm3GpAX990ZmGDeucuF8nBw-hE4JviaYkpt-pRWmlPMdNCGC4lxiKnbRBBPJclZIfoAOY3zHGDOsxT7a11wSKdUEiWn2MAbofVtnJVQ19C67awcXVi5dTfBdNvMDdP7NDb7Pel_7OMZjtNfAMrqTzXuEXh_uF7dPefny-Hw7LXNgWg85q3AjuK4LkJar2oGCgjZEKQbKQiV4IQVW1BImOBG6ohw0E41SklSFrSt2hC7XvavgP0cXB9O10brlMs30YzRKy4IyTRJ4tQZt8DEG15hVaDsI34Zg86vIbBUl9mxTOladq7fkxknKzzc5RAvLJtmxbdxilCQOs4Tla6yNg_vaxhA-TCpRwixmcyPKefkodWHE37cNeANvIVW-zolOqyQXQqf8Yp2Djebdj6FPZv-Z_wPtVo85</recordid><startdate>19980101</startdate><enddate>19980101</enddate><creator>Qais, Nazmul</creator><creator>Mandal, Mushfiqur Rahman</creator><creator>Rashid, Mohammad Abdur</creator><creator>Jabbar, Abdul</creator><creator>Koshino, Hiroyuki</creator><creator>Nagasawa, Kazuo</creator><creator>Nakata, Tadashi</creator><general>American Chemical Society</general><general>American Society of Pharmacognosy</general><scope>FBQ</scope><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19980101</creationdate><title>A Furanoid Labdane Diterpene from Potamogeton nodosus</title><author>Qais, Nazmul ; Mandal, Mushfiqur Rahman ; Rashid, Mohammad Abdur ; Jabbar, Abdul ; Koshino, Hiroyuki ; Nagasawa, Kazuo ; Nakata, Tadashi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a399t-3b0f549d8a6c47dea7a82f1773a7cab54865072c1354159b24a935f7761b8cdb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Anti-Bacterial Agents - isolation & purification</topic><topic>Anti-Bacterial Agents - pharmacology</topic><topic>AQUATIC PLANTS</topic><topic>BACTERICIDAS</topic><topic>BACTERICIDE</topic><topic>BACTERICIDES</topic><topic>BANGLADESH</topic><topic>Biological and medical sciences</topic><topic>CHEMICAL COMPOSITION</topic><topic>CHEMICAL STRUCTURE</topic><topic>COMPOSICION QUIMICA</topic><topic>COMPOSITION CHIMIQUE</topic><topic>DITERPENOIDE</topic><topic>DITERPENOIDS</topic><topic>DITERPENOS</topic><topic>DRUG PLANTS</topic><topic>ESPECTROMETRIA</topic><topic>ESTRUCTURA QUIMICA</topic><topic>General pharmacology</topic><topic>Gram-Negative Bacteria - drug effects</topic><topic>Gram-Positive Bacteria - drug effects</topic><topic>India</topic><topic>Magnetic Resonance Spectroscopy</topic><topic>Medical sciences</topic><topic>Microbial Sensitivity Tests</topic><topic>Pharmacognosy. 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Nat. Prod</addtitle><date>1998-01-01</date><risdate>1998</risdate><volume>61</volume><issue>1</issue><spage>156</spage><epage>157</epage><pages>156-157</pages><issn>0163-3864</issn><eissn>1520-6025</eissn><coden>JNPRDF</coden><abstract>A new furanoid diterpene, 15,16-epoxy-12-oxo-8(17),13(16),14-labdatrien-20,19-olide (1) was isolated from an ethanolic extract of Potamogeton nodosus. Its structure was elucidated by the usual spectroscopic methods, including 2D NMR techniques. Compound 1 was found to exhibit moderate inhibitory activity against a number of both Gram-positive and Gram-negative bacteria.</abstract><cop>Washington, DC</cop><cop>Glendale, AZ</cop><pub>American Chemical Society</pub><pmid>9461667</pmid><doi>10.1021/np9702244</doi><tpages>2</tpages></addata></record> |
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subjects | Anti-Bacterial Agents - isolation & purification Anti-Bacterial Agents - pharmacology AQUATIC PLANTS BACTERICIDAS BACTERICIDE BACTERICIDES BANGLADESH Biological and medical sciences CHEMICAL COMPOSITION CHEMICAL STRUCTURE COMPOSICION QUIMICA COMPOSITION CHIMIQUE DITERPENOIDE DITERPENOIDS DITERPENOS DRUG PLANTS ESPECTROMETRIA ESTRUCTURA QUIMICA General pharmacology Gram-Negative Bacteria - drug effects Gram-Positive Bacteria - drug effects India Magnetic Resonance Spectroscopy Medical sciences Microbial Sensitivity Tests Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments PLANTAS ACUATICAS PLANTAS MEDICINALES PLANTE AQUATIQUE PLANTE MEDICINALE Plants, Medicinal - chemistry POTAMOGETON RACINE RAICES ROOTS SPECTRAL ANALYSIS SPECTROMETRIE SPECTROMETRY STRUCTURE CHIMIQUE |
title | A Furanoid Labdane Diterpene from Potamogeton nodosus |
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