Mutations in the CDKN2A ( p16INK4a ) gene in microdissected sporadic primary melanomas

The role of the CDKN2A (p16INK4a) gene in sporadic primary melanomas has remained unclear due to the inadequate number of mutational studies. In the present study, we analyzed the entire coding region of the CDKN2A gene in microdissected sporadic primary melanomas, for the presence of mutations and...

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Veröffentlicht in:	International journal of cancer 1998-01, Vol.75 (2), p.193-198
Hauptverfasser:	Kumar, Rajiv, Rozell, Barbro Lundh, Louhelainen, Jari, Hemminki, Kari
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cyclin-Dependent Kinase Inhibitor p16 - genetics Dermatology Dissection Humans Medical sciences Melanoma - genetics Mutation Polymorphism, Genetic Skin Neoplasms - genetics Tumors of the skin and soft tissue. Premalignant lesions
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