A new reciprocal translocation (12;22)(q24.3;q11.2–12) in a malignant rhabdoid tumor of the brain

We report a malignant rhabdoid tumor (MRT) of the brain with a novel reciprocal translocation, t(12;22)(q24.3;q11.2–12). Previous reports of chromosome abnormalities in MRTs were characterized either by monosomy or partial deletions of chromosome 22. An unbalanced translocation has been identified i...

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Veröffentlicht in:	Cancer genetics and cytogenetics 1998-02, Vol.101 (1), p.62-67
Hauptverfasser:	Sawyer, Jeffrey R., Goosen, Linda S., Swanson, Charles M., Tomita, Tadanori, de Leon, Guillermo A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Brain Neoplasms - genetics Brain Neoplasms - pathology Child, Preschool Chromosome Banding Chromosomes, Human, Pair 12 Chromosomes, Human, Pair 22 Humans Karyotyping Medical sciences Neurology Rhabdoid Tumor - genetics Rhabdoid Tumor - pathology Translocation, Genetic Tumors of the nervous system. Phacomatoses
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