Molecular evolution of the aldo-keto reductase gene superfamily

The aldo-keto reductase enzymes comprise a functionally diverse gene family which catalyze the NADPH-dependant reduction of a variety of carbonyl compounds. The protein sequences of 45 members of this family were aligned and phylogenetic trees were deduced from this alignment using the neighbor-join...

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Veröffentlicht in:	Journal of molecular evolution 1998-02, Vol.46 (2), p.139-146
Hauptverfasser:	Seery, L T, Nestor, P V, FitzGerald, G A
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Oxidoreductases - chemistry Alcohol Oxidoreductases - genetics Aldehyde Reductase Aldo-Keto Reductases Evolution, Molecular Phylogeny Sequence Alignment
Online-Zugang:	Volltext
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