Diabetic Retinopathy: A Synthesis of Perspectives
IT is estimated that 5000 patients with diabetes in the United States and 30,000 to 40,000 worldwide become blind each year from retinopathy. Despite advances in the use of photocoagulation and vitrectomy, diabetic retinopathy has been the leading cause of blindness in Great Britain, North America,...
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Veröffentlicht in: | The New England journal of medicine 1990-04, Vol.322 (14), p.978-983 |
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container_title | The New England journal of medicine |
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creator | Merimee, Thomas J |
description | IT is estimated that 5000 patients with diabetes in the United States and 30,000 to 40,000 worldwide become blind each year from retinopathy. Despite advances in the use of photocoagulation and vitrectomy, diabetic retinopathy has been the leading cause of blindness in Great Britain, North America, Europe, and Scandinavia since 1974.
1
The sequence of anatomical changes in the retina leading to blindness in diabetes is fairly well defined,
2
3
4
but the causes are poorly understood. Most components of diabetic retinopathy, including endothelial proliferation, capillary closure, and preretinal neovascularization, occur in other diseases. However, the constellation of lesions, from early thickening of . . . |
doi_str_mv | 10.1056/NEJM199004053221406 |
format | Article |
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1
The sequence of anatomical changes in the retina leading to blindness in diabetes is fairly well defined,
2
3
4
but the causes are poorly understood. Most components of diabetic retinopathy, including endothelial proliferation, capillary closure, and preretinal neovascularization, occur in other diseases. However, the constellation of lesions, from early thickening of . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJM199004053221406</identifier><identifier>PMID: 2179725</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>Boston, MA: Massachusetts Medical Society</publisher><subject>Biological and medical sciences ; Diabetic Retinopathy - etiology ; Endocrinopathies ; Humans ; Medical sciences</subject><ispartof>The New England journal of medicine, 1990-04, Vol.322 (14), p.978-983</ispartof><rights>1993 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c230t-825d4abd898d615772b76293ef8eca68b1f139521fff6b6585ef3a4cc05ef2fd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJM199004053221406$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJM199004053221406$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>314,780,784,2759,2760,26103,27924,27925,52382,54064,64387</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4619159$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2179725$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Merimee, Thomas J</creatorcontrib><title>Diabetic Retinopathy: A Synthesis of Perspectives</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>IT is estimated that 5000 patients with diabetes in the United States and 30,000 to 40,000 worldwide become blind each year from retinopathy. Despite advances in the use of photocoagulation and vitrectomy, diabetic retinopathy has been the leading cause of blindness in Great Britain, North America, Europe, and Scandinavia since 1974.
1
The sequence of anatomical changes in the retina leading to blindness in diabetes is fairly well defined,
2
3
4
but the causes are poorly understood. Most components of diabetic retinopathy, including endothelial proliferation, capillary closure, and preretinal neovascularization, occur in other diseases. However, the constellation of lesions, from early thickening of . . .</description><subject>Biological and medical sciences</subject><subject>Diabetic Retinopathy - etiology</subject><subject>Endocrinopathies</subject><subject>Humans</subject><subject>Medical sciences</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtLAzEQxoMotVZv3kTwIF5kNZN3jqXWF1VB9Byy2QS37KNutof-90a69CTOYWZgft83zCB0BvgGMBe3r_PnF9AaY4Y5JQQYFntoDJzSjKV-H40xJipjUtNDdBTjEqcApkdoREBqSfgYnd6VNvd96S7eU27ale2_NsfoINgq-pOhTtDn_fxj9pgt3h6eZtNF5gjFfaYIL5jNC6VVIYBLSXIpiKY-KO-sUDkEoJoTCCGIXHDFfaCWOYdTQ0JBJ-hq67vq2u-1j72py-h8VdnGt-topBZSMIoTSLeg69oYOx_Mqitr220MYPP7C_PHL5LqfLBf57Uvdprh-DS_HOY2OluFzjaujDuMCdDAdcKut1hdR9P4Zf3v0h8gI3Ba</recordid><startdate>19900405</startdate><enddate>19900405</enddate><creator>Merimee, Thomas J</creator><general>Massachusetts Medical Society</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19900405</creationdate><title>Diabetic Retinopathy</title><author>Merimee, Thomas J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c230t-825d4abd898d615772b76293ef8eca68b1f139521fff6b6585ef3a4cc05ef2fd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Biological and medical sciences</topic><topic>Diabetic Retinopathy - etiology</topic><topic>Endocrinopathies</topic><topic>Humans</topic><topic>Medical sciences</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Merimee, Thomas J</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Merimee, Thomas J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Diabetic Retinopathy: A Synthesis of Perspectives</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>1990-04-05</date><risdate>1990</risdate><volume>322</volume><issue>14</issue><spage>978</spage><epage>983</epage><pages>978-983</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><coden>NEJMAG</coden><abstract>IT is estimated that 5000 patients with diabetes in the United States and 30,000 to 40,000 worldwide become blind each year from retinopathy. Despite advances in the use of photocoagulation and vitrectomy, diabetic retinopathy has been the leading cause of blindness in Great Britain, North America, Europe, and Scandinavia since 1974.
1
The sequence of anatomical changes in the retina leading to blindness in diabetes is fairly well defined,
2
3
4
but the causes are poorly understood. Most components of diabetic retinopathy, including endothelial proliferation, capillary closure, and preretinal neovascularization, occur in other diseases. However, the constellation of lesions, from early thickening of . . .</abstract><cop>Boston, MA</cop><pub>Massachusetts Medical Society</pub><pmid>2179725</pmid><doi>10.1056/NEJM199004053221406</doi><tpages>6</tpages></addata></record> |
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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; ProQuest Central UK/Ireland; New England Journal of Medicine |
subjects | Biological and medical sciences Diabetic Retinopathy - etiology Endocrinopathies Humans Medical sciences |
title | Diabetic Retinopathy: A Synthesis of Perspectives |
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