A “Septide‐Sensitive” Receptor Is Not Involved in Tachykinin‐Mediated Secretory and Inositol Phosphate Responses in Rat Parotid Gland: Are Several Transduction Pathways Involved After the Stimulation of the NK1 Receptor?

: In the rat parotid gland, the neuropeptide substance P (SP), as well as SP(4–11), and septide elicited inositol phosphate production (EC50 values 0.44, 2, and 20 nM, respectively). No additivity of the maximal response to the three agonists was observed. SP, SP(4–11), and septide also stimulated p...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of neurochemistry 1998-02, Vol.70 (2), p.858-864
Hauptverfasser:	Huleux, Claire, Berthier, Annabel, Rossignol, Bernard, Dreux, Catherine
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cells, Cultured Fundamental and applied biological sciences. Psychology Indoles - pharmacology Inositol phosphates Inositol Phosphates - metabolism Isoindoles Kinetics Male Neurokinin-1 Receptor Antagonists Parotid Gland - cytology Parotid Gland - drug effects Parotid Gland - physiology Parotid glands Peptide Fragments - pharmacology Protein secretion Pyrrolidonecarboxylic Acid - analogs & derivatives Rats Rats, Sprague-Dawley Receptors, Neurokinin-1 - drug effects Receptors, Neurokinin-1 - physiology RP67580 Salivary Proteins and Peptides - biosynthesis Septide Signal Transduction - drug effects Signal Transduction - physiology Substance P Substance P - analogs & derivatives Substance P - pharmacology Substance P(4–11) Tachykinins - pharmacology Vertebrates: skin, associated glands, phaneres, light organs, various exocrine glands (salt gland, uropygial gland...), adipose tissue, connective tissue
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!