Muscarinic cholinoceptors in the human heart: demonstration, subclassification, and distribution

In human atrial and ventricular myocardium, the muscarinic cholinoceptor (M-cholinoceptor) populations were characterized by means of radioligand binding (with [N-methyl-3H]-scopolamine ([3H]-NMS) as the ligand) and functional experiments (negative inotropic effect of carbachol on isolated electrica...

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Veröffentlicht in:	Naunyn-Schmiedeberg's archives of pharmacology 1990, Vol.341 (1-2), p.14-21
Hauptverfasser:	DEIGHTON, N. M, MOTOMURA, S, BORQUEZ, D, ZERBOWSKI, H.-R, DOETSCH, N, BRODDE, O.-E
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Carbachol - pharmacology Electric Stimulation Fundamental and applied biological sciences. Psychology Heart Heart - drug effects Humans In Vitro Techniques Kinetics Membranes - drug effects Membranes - metabolism Myocardial Contraction - drug effects Myocardium - metabolism N-Methylscopolamine Papillary Muscles - drug effects Papillary Muscles - metabolism Piperidines - pharmacology Pirenzepine - analogs & derivatives Pirenzepine - pharmacology Radioligand Assay Receptors, Muscarinic - metabolism Scopolamine Derivatives Vertebrates: cardiovascular system
Online-Zugang:	Volltext
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