Duodenal biopsies of HIV-infected patients with diarrhoea exhibit epithelial barrier defects but no active secretion

To characterize diarrhoeal mechanisms in HIV-infected patients, epithelial transport and barrier function of the duodenal mucosa was investigated in vitro. Twenty-one HIV-seropositive patients (13 asymptomatic and eight with diarrhoea) and 12 controls from an urban referral-based tertiary care centr...

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Veröffentlicht in:	AIDS (London) 1998, Vol.12 (1), p.43-51
Hauptverfasser:	STOCKMANN, M, FROMM, M, SCHMITZ, H, SCHMIDT, W, RIECKEN, E.-O, SCHULZKE, J.-D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged AIDS/HIV Biological and medical sciences Biological Transport Biopsy - methods Bumetanide - pharmacology Chlorides - metabolism Diarrhea - complications Diarrhea - physiopathology Diuretics - pharmacology Duodenum - physiopathology Electric Impedance Glucose - pharmacokinetics HIV Infections - complications HIV Infections - physiopathology Human viral diseases Humans In Vitro Techniques Infectious diseases Intestinal Mucosa - physiopathology Lactulose - pharmacokinetics Malabsorption Syndromes - virology Mannitol - pharmacokinetics Medical sciences Middle Aged Permeability Phlorhizin - pharmacology Sodium - pharmacokinetics Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids
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