Nefopam Hydrochloride Degradation Kinetics in Solution

A stability-indicating reversed-phase high performance liquid chromatographic method was developed for the detection of nefopam hydrochloride and its degradation products under accelerated degradation conditions. The degradation kinetics of nefopam hydrochloride in aqueous solutions over a pH range...

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Veröffentlicht in:	Journal of pharmaceutical sciences 1990-01, Vol.79 (1), p.48-52
Hauptverfasser:	Tu, Yu-Hsing, Wang, Da-Peng, Allen, Loyd V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics Biological and medical sciences Buffers Chromatography, High Pressure Liquid Drug Stability Hydrogen-Ion Concentration Medical sciences Nefopam - pharmacokinetics Nefopam - radiation effects Neuropharmacology Oxazocines - pharmacokinetics Pharmacology. Drug treatments Polyethylene Glycols Propylene Glycols Solutions Solvents Temperature Ultraviolet Rays
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