Illegitimate transcription: its use for studying genetic abnormalities in lymphoblastoid cells from patients with Glanzmann thrombasthenia

Glanzmann thrombasthenia is the most common inherited disorder of platelets that may induce severe bleeding complications. Molecular biology techniques have offered the possibility to assess the basis of this chronic haemorrhagic disease at the molecular level. However, the accessibility of mRNA in...

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Veröffentlicht in:	British journal of haematology 1998-01, Vol.100 (1), p.33-39
Hauptverfasser:	Negrier, Claude, Vinciguerra, Christine, Attali, Olivier, Grenier, Christine, Larcher, Marie Estelle, Dechavanne, Marc
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, CD - metabolism B-Lymphocytes - metabolism Biological and medical sciences Blood Platelets - physiology Cell Line, Transformed ectopic transcription Flow Cytometry Glanzmann thrombasthenia glycoprotein IIb–IIIa Hematologic and hematopoietic diseases Humans illegitimate transcription lymphoblastoid cells Medical sciences Mutation Platelet diseases and coagulopathies Platelet Glycoprotein GPIIb-IIIa Complex - genetics RNA, Messenger - analysis Thrombasthenia - genetics Transcription, Genetic
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