Hex: a homeobox gene revealing peri-implantation asymmetry in the mouse embryo and an early transient marker of endothelial cell precursors

The divergent homeobox gene Hex exhibits three notable expression patterns during early mouse development. Initially Hex is expressed in the primitive endoderm of the implanting blastocyst but by 5.5 dpc its transcripts are present only in a small patch of visceral endoderm at the distal tip of the...

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Veröffentlicht in:	Development (Cambridge) 1998-01, Vol.125 (1), p.85-94
Hauptverfasser:	Thomas, P Q, Brown, A, Beddington, R S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Body Patterning Carbocyanines - metabolism Cell Differentiation Digestive System - embryology Embryo, Mammalian - metabolism Embryonic and Fetal Development Endoderm - physiology Endothelium, Vascular - cytology Endothelium, Vascular - embryology Gastrula - physiology Gene Expression Regulation, Developmental Genes, Homeobox - genetics Histocytochemistry Homeodomain Proteins - genetics In Situ Hybridization Mice Neovascularization, Physiologic Receptor Protein-Tyrosine Kinases - genetics Receptors, Growth Factor - genetics Receptors, Vascular Endothelial Growth Factor RNA, Messenger - analysis Stem Cells - cytology Transcription Factors
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