(+)‐[3H]MK‐801 Binding Sites in Postmortem Human Brain

: The pharmacological specificity and the regional distribution of the N‐methyl‐D‐aspartate receptor‐associated 5‐methyl‐10,11‐dihydro‐5H‐dibenzo[a,d]cyclohepten‐5, 10‐imine maleate (MK‐801) binding sites in human postmortem brain tissue were determined by binding studies using (+)‐[3H]MK‐801. Scatc...

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Veröffentlicht in:	Journal of neurochemistry 1990-04, Vol.54 (4), p.1163-1168
Hauptverfasser:	Quarum, Merrit L., Parker, Joel D., Keana, John F. W., Weber, Eckard
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Anticonvulsants Aspartic Acid - analogs & derivatives Aspartic Acid - physiology Binding Sites Binding, Competitive Biological and medical sciences Brain - metabolism Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Dibenzocycloheptenes - metabolism Dizocilpine Maleate Female Fundamental and applied biological sciences. Psychology Human Humans Male Middle Aged MK‐801 N-Methylaspartate N‐Methyl‐D‐aspartate Phencyclidine Postmortem Changes Receptor Receptors, Neurotransmitter - metabolism Receptors, Phencyclidine Stereoisomerism Tissue Distribution Tritium Vertebrates: nervous system and sense organs
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