Precursors for Cholesterol Synthesis (7‐Dehydrocholesterol, 7‐Dehydrodesmosterol, and Desmosterol): Cholesterol/7‐Dehydrocholesterol Ratio as an Index of Development and Aging in PNS but Not in CNS

: In rat sciatic nerve, the 7‐dehydrocholesterol content decreased dramatically during the postnatal period and slowly during adulthood and aging. In contrast, the 7‐dehydrodesmosterol content peaked at 14 days and was nearly undetectable after 60 days. The desmosterol content peaked at 21 days and...

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Veröffentlicht in:	Journal of neurochemistry 1990-04, Vol.54 (4), p.1196-1199
Hauptverfasser:	Bourre, J. M., Clément, M., Gérard, D., Legrand, R., Chaudière, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	7‐Dehydrocholesterol 7‐Dehydrodesmosterol Aging Aging - metabolism Animals Animals, Newborn Biochemistry and metabolism Biological and medical sciences Brain Brain - growth & development Brain - metabolism Central nervous system Cholecalciferol - metabolism Cholestadienols - metabolism Cholesterol Cholesterol - biosynthesis Cholesterol - metabolism CNS Dehydrocholesterols - metabolism Desmosterol Desmosterol - metabolism Development Fundamental and applied biological sciences. Psychology Peripheral Nerves - growth & development Peripheral Nerves - metabolism PNS Prodrugs - metabolism Rats Rats, Inbred Strains Sciatic nerve Sciatic Nerve - metabolism Vertebrates: nervous system and sense organs
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