Staging of invasive cervical carcinoma and of pelvic lymph nodes by high resolution MRI with a phased-array coil in comparison with pathological findings
Our goal was to stage invasive cervical carcinoma (pT1b-pT4a) and pelvic lymph nodes by high resolution MRI with a circularly polarized (cp) phased-array coil in correlation with the whole-mount specimen and the histopathological findings. Thirty-three patients (20-68 years old; mean age 55 years) w...
Gespeichert in:
| Veröffentlicht in: | Journal of computer assisted tomography 1998, Vol.22 (1), p.75-81 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 81 |
|---|---|
| container_issue | 1 |
| container_start_page | 75 |
| container_title | Journal of computer assisted tomography |
| container_volume | 22 |
| creator | HAWIGHORST, H SCHOENBERG, S. O KNAPSTEIN, P. G KNOPP, M. V SCHAEFFER, U ESSIG, M VAN KAICK, G |
| description | Our goal was to stage invasive cervical carcinoma (pT1b-pT4a) and pelvic lymph nodes by high resolution MRI with a circularly polarized (cp) phased-array coil in correlation with the whole-mount specimen and the histopathological findings.
Thirty-three patients (20-68 years old; mean age 55 years) with biopsy-proven primary cancer of the cervix were prospectively examined on a 1.5 T scanner by using a cp body phased-array coil. The MR protocol consisted of high resolution T2-weighted turbo-SE (TSE) and pre- and postcontrast T1-weighted SE (SE) sequences. Slice thickness was 5-7 mm with a pixel size of 0.3-0.4 mm2. All MRI findings were matched to the whole-mount specimens and the histopathological findings.
Pathological stages evaluated were pT1b (n = 5), pT2b (n = 16), and pT4a (n = 12). The overall accuracy rates for tumor staging were 79% for high resolution T2-weighted TSE and 76% for postcontrast T1-weighted SE images. The accuracy for high resolution T2-weighted TSE images in determining parametrial infiltration, pelvic side wall, and bladder and rectal wall infiltration was 84, 87, and 87%, respectively. In prospective analysis of the 1.0 cm criterion for diagnosis of a positive pelvic lymph node, MRI had a 72% accuracy, a 68% sensitivity, and a 78% specificity.
High resolution MRI with a cp body phased-array coil provides excellent and robust high resolution images in patients with invasive cervical carcinoma. However, accuracy, specificity, and sensitivity for staging invasive cervical carcinoma and pelvic lymph nodes with correlation to whole-mount specimens and histopathological findings did not improve compared with the results in the literature using a body coil with thicker slices and a lower spatial resolution. |
| doi_str_mv | 10.1097/00004728-199801000-00013 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_79665849</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>79665849</sourcerecordid><originalsourceid>FETCH-LOGICAL-c339t-f3d2f5783d9b73d9a2b91b317e4ac636ba8e6b74bfd0aef22eb23cef79435f673</originalsourceid><addsrcrecordid>eNo9kdFuFCEUhomxqWv1EUy4MN6NDnOYYbg0jdUmNSa2Xk8ODOxgGBhhds0-im9bul2XBE7I_53zE35CKKs_slqKT3VZXDR9xaTsa1ZuVdkMXpANa6GpgPH2JdnU0EHVC9a-Iq9z_l0IAcAvyaXkvBdduyH_7lfcurCl0VIX9pjd3lBt0t5p9FRj0i7EGSmG8QlZjC8K9Yd5mWiIo8lUHejkthNNJke_W10M9PvPW_rXrRNFukyYzVhhSnigOjpfXEqdF0wuF_SILbhO0cft0dO6MJYH5TfkwqLP5u2pXpFfN18err9Vdz--3l5_vqs0gFwrC2NjW9HDKJUoBzZKMgVMGI66g05hbzoluLJjjcY2jVENaGOF5NDaTsAV-fA8d0nxz87kdZhd1sZ7DCbu8iBk17U9lwXsn0GdYs7J2GFJbsZ0GFg9PKUy_E9lOKcyHFMpre9OHjs1m_HceIqh6O9POubyBzZh0C6fsYYBYyDhEcvYmBs</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>79665849</pqid></control><display><type>article</type><title>Staging of invasive cervical carcinoma and of pelvic lymph nodes by high resolution MRI with a phased-array coil in comparison with pathological findings</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><creator>HAWIGHORST, H ; SCHOENBERG, S. O ; KNAPSTEIN, P. G ; KNOPP, M. V ; SCHAEFFER, U ; ESSIG, M ; VAN KAICK, G</creator><creatorcontrib>HAWIGHORST, H ; SCHOENBERG, S. O ; KNAPSTEIN, P. G ; KNOPP, M. V ; SCHAEFFER, U ; ESSIG, M ; VAN KAICK, G</creatorcontrib><description>Our goal was to stage invasive cervical carcinoma (pT1b-pT4a) and pelvic lymph nodes by high resolution MRI with a circularly polarized (cp) phased-array coil in correlation with the whole-mount specimen and the histopathological findings.
Thirty-three patients (20-68 years old; mean age 55 years) with biopsy-proven primary cancer of the cervix were prospectively examined on a 1.5 T scanner by using a cp body phased-array coil. The MR protocol consisted of high resolution T2-weighted turbo-SE (TSE) and pre- and postcontrast T1-weighted SE (SE) sequences. Slice thickness was 5-7 mm with a pixel size of 0.3-0.4 mm2. All MRI findings were matched to the whole-mount specimens and the histopathological findings.
Pathological stages evaluated were pT1b (n = 5), pT2b (n = 16), and pT4a (n = 12). The overall accuracy rates for tumor staging were 79% for high resolution T2-weighted TSE and 76% for postcontrast T1-weighted SE images. The accuracy for high resolution T2-weighted TSE images in determining parametrial infiltration, pelvic side wall, and bladder and rectal wall infiltration was 84, 87, and 87%, respectively. In prospective analysis of the 1.0 cm criterion for diagnosis of a positive pelvic lymph node, MRI had a 72% accuracy, a 68% sensitivity, and a 78% specificity.
High resolution MRI with a cp body phased-array coil provides excellent and robust high resolution images in patients with invasive cervical carcinoma. However, accuracy, specificity, and sensitivity for staging invasive cervical carcinoma and pelvic lymph nodes with correlation to whole-mount specimens and histopathological findings did not improve compared with the results in the literature using a body coil with thicker slices and a lower spatial resolution.</description><identifier>ISSN: 0363-8715</identifier><identifier>EISSN: 1532-3145</identifier><identifier>DOI: 10.1097/00004728-199801000-00013</identifier><identifier>PMID: 9448765</identifier><identifier>CODEN: JCATD5</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott</publisher><subject>Adult ; Aged ; Biological and medical sciences ; Biopsy ; Carcinoma - diagnosis ; Carcinoma - secondary ; Carcinoma in Situ ; Female ; Genital system. Mammary gland ; Humans ; Image Enhancement ; Investigative techniques, diagnostic techniques (general aspects) ; Lymph Nodes - pathology ; Lymphatic Metastasis ; Magnetic Resonance Imaging ; Medical sciences ; Middle Aged ; Neoplasm Invasiveness ; Neoplasm Staging ; Pelvis ; Predictive Value of Tests ; Prospective Studies ; Radiodiagnosis. Nmr imagery. Nmr spectrometry ; Rectal Neoplasms - diagnosis ; Sensitivity and Specificity ; Urinary Bladder Neoplasms - diagnosis ; Uterine Cervical Neoplasms - diagnosis</subject><ispartof>Journal of computer assisted tomography, 1998, Vol.22 (1), p.75-81</ispartof><rights>1998 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c339t-f3d2f5783d9b73d9a2b91b317e4ac636ba8e6b74bfd0aef22eb23cef79435f673</citedby><cites>FETCH-LOGICAL-c339t-f3d2f5783d9b73d9a2b91b317e4ac636ba8e6b74bfd0aef22eb23cef79435f673</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,4010,27904,27905,27906</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2131139$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9448765$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>HAWIGHORST, H</creatorcontrib><creatorcontrib>SCHOENBERG, S. O</creatorcontrib><creatorcontrib>KNAPSTEIN, P. G</creatorcontrib><creatorcontrib>KNOPP, M. V</creatorcontrib><creatorcontrib>SCHAEFFER, U</creatorcontrib><creatorcontrib>ESSIG, M</creatorcontrib><creatorcontrib>VAN KAICK, G</creatorcontrib><title>Staging of invasive cervical carcinoma and of pelvic lymph nodes by high resolution MRI with a phased-array coil in comparison with pathological findings</title><title>Journal of computer assisted tomography</title><addtitle>J Comput Assist Tomogr</addtitle><description>Our goal was to stage invasive cervical carcinoma (pT1b-pT4a) and pelvic lymph nodes by high resolution MRI with a circularly polarized (cp) phased-array coil in correlation with the whole-mount specimen and the histopathological findings.
Thirty-three patients (20-68 years old; mean age 55 years) with biopsy-proven primary cancer of the cervix were prospectively examined on a 1.5 T scanner by using a cp body phased-array coil. The MR protocol consisted of high resolution T2-weighted turbo-SE (TSE) and pre- and postcontrast T1-weighted SE (SE) sequences. Slice thickness was 5-7 mm with a pixel size of 0.3-0.4 mm2. All MRI findings were matched to the whole-mount specimens and the histopathological findings.
Pathological stages evaluated were pT1b (n = 5), pT2b (n = 16), and pT4a (n = 12). The overall accuracy rates for tumor staging were 79% for high resolution T2-weighted TSE and 76% for postcontrast T1-weighted SE images. The accuracy for high resolution T2-weighted TSE images in determining parametrial infiltration, pelvic side wall, and bladder and rectal wall infiltration was 84, 87, and 87%, respectively. In prospective analysis of the 1.0 cm criterion for diagnosis of a positive pelvic lymph node, MRI had a 72% accuracy, a 68% sensitivity, and a 78% specificity.
High resolution MRI with a cp body phased-array coil provides excellent and robust high resolution images in patients with invasive cervical carcinoma. However, accuracy, specificity, and sensitivity for staging invasive cervical carcinoma and pelvic lymph nodes with correlation to whole-mount specimens and histopathological findings did not improve compared with the results in the literature using a body coil with thicker slices and a lower spatial resolution.</description><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Biopsy</subject><subject>Carcinoma - diagnosis</subject><subject>Carcinoma - secondary</subject><subject>Carcinoma in Situ</subject><subject>Female</subject><subject>Genital system. Mammary gland</subject><subject>Humans</subject><subject>Image Enhancement</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Lymph Nodes - pathology</subject><subject>Lymphatic Metastasis</subject><subject>Magnetic Resonance Imaging</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neoplasm Invasiveness</subject><subject>Neoplasm Staging</subject><subject>Pelvis</subject><subject>Predictive Value of Tests</subject><subject>Prospective Studies</subject><subject>Radiodiagnosis. Nmr imagery. Nmr spectrometry</subject><subject>Rectal Neoplasms - diagnosis</subject><subject>Sensitivity and Specificity</subject><subject>Urinary Bladder Neoplasms - diagnosis</subject><subject>Uterine Cervical Neoplasms - diagnosis</subject><issn>0363-8715</issn><issn>1532-3145</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kdFuFCEUhomxqWv1EUy4MN6NDnOYYbg0jdUmNSa2Xk8ODOxgGBhhds0-im9bul2XBE7I_53zE35CKKs_slqKT3VZXDR9xaTsa1ZuVdkMXpANa6GpgPH2JdnU0EHVC9a-Iq9z_l0IAcAvyaXkvBdduyH_7lfcurCl0VIX9pjd3lBt0t5p9FRj0i7EGSmG8QlZjC8K9Yd5mWiIo8lUHejkthNNJke_W10M9PvPW_rXrRNFukyYzVhhSnigOjpfXEqdF0wuF_SILbhO0cft0dO6MJYH5TfkwqLP5u2pXpFfN18err9Vdz--3l5_vqs0gFwrC2NjW9HDKJUoBzZKMgVMGI66g05hbzoluLJjjcY2jVENaGOF5NDaTsAV-fA8d0nxz87kdZhd1sZ7DCbu8iBk17U9lwXsn0GdYs7J2GFJbsZ0GFg9PKUy_E9lOKcyHFMpre9OHjs1m_HceIqh6O9POubyBzZh0C6fsYYBYyDhEcvYmBs</recordid><startdate>1998</startdate><enddate>1998</enddate><creator>HAWIGHORST, H</creator><creator>SCHOENBERG, S. O</creator><creator>KNAPSTEIN, P. G</creator><creator>KNOPP, M. V</creator><creator>SCHAEFFER, U</creator><creator>ESSIG, M</creator><creator>VAN KAICK, G</creator><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1998</creationdate><title>Staging of invasive cervical carcinoma and of pelvic lymph nodes by high resolution MRI with a phased-array coil in comparison with pathological findings</title><author>HAWIGHORST, H ; SCHOENBERG, S. O ; KNAPSTEIN, P. G ; KNOPP, M. V ; SCHAEFFER, U ; ESSIG, M ; VAN KAICK, G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c339t-f3d2f5783d9b73d9a2b91b317e4ac636ba8e6b74bfd0aef22eb23cef79435f673</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Biopsy</topic><topic>Carcinoma - diagnosis</topic><topic>Carcinoma - secondary</topic><topic>Carcinoma in Situ</topic><topic>Female</topic><topic>Genital system. Mammary gland</topic><topic>Humans</topic><topic>Image Enhancement</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Lymph Nodes - pathology</topic><topic>Lymphatic Metastasis</topic><topic>Magnetic Resonance Imaging</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Neoplasm Invasiveness</topic><topic>Neoplasm Staging</topic><topic>Pelvis</topic><topic>Predictive Value of Tests</topic><topic>Prospective Studies</topic><topic>Radiodiagnosis. Nmr imagery. Nmr spectrometry</topic><topic>Rectal Neoplasms - diagnosis</topic><topic>Sensitivity and Specificity</topic><topic>Urinary Bladder Neoplasms - diagnosis</topic><topic>Uterine Cervical Neoplasms - diagnosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>HAWIGHORST, H</creatorcontrib><creatorcontrib>SCHOENBERG, S. O</creatorcontrib><creatorcontrib>KNAPSTEIN, P. G</creatorcontrib><creatorcontrib>KNOPP, M. V</creatorcontrib><creatorcontrib>SCHAEFFER, U</creatorcontrib><creatorcontrib>ESSIG, M</creatorcontrib><creatorcontrib>VAN KAICK, G</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of computer assisted tomography</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>HAWIGHORST, H</au><au>SCHOENBERG, S. O</au><au>KNAPSTEIN, P. G</au><au>KNOPP, M. V</au><au>SCHAEFFER, U</au><au>ESSIG, M</au><au>VAN KAICK, G</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Staging of invasive cervical carcinoma and of pelvic lymph nodes by high resolution MRI with a phased-array coil in comparison with pathological findings</atitle><jtitle>Journal of computer assisted tomography</jtitle><addtitle>J Comput Assist Tomogr</addtitle><date>1998</date><risdate>1998</risdate><volume>22</volume><issue>1</issue><spage>75</spage><epage>81</epage><pages>75-81</pages><issn>0363-8715</issn><eissn>1532-3145</eissn><coden>JCATD5</coden><abstract>Our goal was to stage invasive cervical carcinoma (pT1b-pT4a) and pelvic lymph nodes by high resolution MRI with a circularly polarized (cp) phased-array coil in correlation with the whole-mount specimen and the histopathological findings.
Thirty-three patients (20-68 years old; mean age 55 years) with biopsy-proven primary cancer of the cervix were prospectively examined on a 1.5 T scanner by using a cp body phased-array coil. The MR protocol consisted of high resolution T2-weighted turbo-SE (TSE) and pre- and postcontrast T1-weighted SE (SE) sequences. Slice thickness was 5-7 mm with a pixel size of 0.3-0.4 mm2. All MRI findings were matched to the whole-mount specimens and the histopathological findings.
Pathological stages evaluated were pT1b (n = 5), pT2b (n = 16), and pT4a (n = 12). The overall accuracy rates for tumor staging were 79% for high resolution T2-weighted TSE and 76% for postcontrast T1-weighted SE images. The accuracy for high resolution T2-weighted TSE images in determining parametrial infiltration, pelvic side wall, and bladder and rectal wall infiltration was 84, 87, and 87%, respectively. In prospective analysis of the 1.0 cm criterion for diagnosis of a positive pelvic lymph node, MRI had a 72% accuracy, a 68% sensitivity, and a 78% specificity.
High resolution MRI with a cp body phased-array coil provides excellent and robust high resolution images in patients with invasive cervical carcinoma. However, accuracy, specificity, and sensitivity for staging invasive cervical carcinoma and pelvic lymph nodes with correlation to whole-mount specimens and histopathological findings did not improve compared with the results in the literature using a body coil with thicker slices and a lower spatial resolution.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott</pub><pmid>9448765</pmid><doi>10.1097/00004728-199801000-00013</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0363-8715 |
| ispartof | Journal of computer assisted tomography, 1998, Vol.22 (1), p.75-81 |
| issn | 0363-8715 1532-3145 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_79665849 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adult Aged Biological and medical sciences Biopsy Carcinoma - diagnosis Carcinoma - secondary Carcinoma in Situ Female Genital system. Mammary gland Humans Image Enhancement Investigative techniques, diagnostic techniques (general aspects) Lymph Nodes - pathology Lymphatic Metastasis Magnetic Resonance Imaging Medical sciences Middle Aged Neoplasm Invasiveness Neoplasm Staging Pelvis Predictive Value of Tests Prospective Studies Radiodiagnosis. Nmr imagery. Nmr spectrometry Rectal Neoplasms - diagnosis Sensitivity and Specificity Urinary Bladder Neoplasms - diagnosis Uterine Cervical Neoplasms - diagnosis |
| title | Staging of invasive cervical carcinoma and of pelvic lymph nodes by high resolution MRI with a phased-array coil in comparison with pathological findings |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T15%3A55%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Staging%20of%20invasive%20cervical%20carcinoma%20and%20of%20pelvic%20lymph%20nodes%20by%20high%20resolution%20MRI%20with%20a%20phased-array%20coil%20in%20comparison%20with%20pathological%20findings&rft.jtitle=Journal%20of%20computer%20assisted%20tomography&rft.au=HAWIGHORST,%20H&rft.date=1998&rft.volume=22&rft.issue=1&rft.spage=75&rft.epage=81&rft.pages=75-81&rft.issn=0363-8715&rft.eissn=1532-3145&rft.coden=JCATD5&rft_id=info:doi/10.1097/00004728-199801000-00013&rft_dat=%3Cproquest_cross%3E79665849%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=79665849&rft_id=info:pmid/9448765&rfr_iscdi=true |