Refinement of the BCL2/immunoglobulin heavy chain fusion gene in t(14;18)(q32;q21) by polymerase chain reaction amplification for long targets

The t(14;18)(q32;q21) translocation, involving the BCL2 gene and junctional segments (JH) of the immunoglobulin heavy chain gene (IGH), constitutes the most common chromosomal translocation in non‐Hodgkin's lymphoma of B‐cell type. Although the breakpoints in BCL2 are largely clustered within t...

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Veröffentlicht in:	Genes chromosomes & cancer 1998-01, Vol.21 (1), p.17-29
Hauptverfasser:	Akasaka, Takashi, Akasaka, Hiroshi, Yonetani, Noboru, Ohno, Hitoshi, Yamabe, Hirohiko, Fukuhara, Shirou, Okuma, Minoru
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Chromosomes, Human, Pair 14 Chromosomes, Human, Pair 18 Deoxyribonucleases, Type II Site-Specific Genes, bcl-2 Genes, Immunoglobulin Humans Immunoglobulin Class Switching Immunoglobulin Heavy Chains Immunoglobulin J-Chains - analysis Lymphoma, Non-Hodgkin - genetics Molecular Sequence Data Polymerase Chain Reaction Restriction Mapping Translocation, Genetic
Online-Zugang:	Volltext
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