Plasma Insulin-Like Growth Factor-I and Prostate Cancer Risk: A Prospective Study

Insulin-like growth factor-I (IGF-I) is a mitogen for prostate epithelial cells. To investigate associations between plasma IGF levels and prostate cancer risk, a nested case-control study within the Physicians' Health Study was conducted on prospectively collected plasma from 152 cases and 152...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1998-01, Vol.279 (5350), p.563-566
Hauptverfasser:	Chan, June M., Stampfer, Meir J., Giovannucci, Edward, Gann, Peter H., Ma, Jing, Wilkinson, Peter, Hennekens, Charles H., Pollak, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Analysis of Variance Anti smoking movements Biological and medical sciences Blood Blood plasma Blood specimen collection Body Composition Body mass index Cancer Case-Control Studies Cell growth Cellular biology Confidence Intervals Diagnosis Disease Susceptibility Estrogens Growth factors Gynecology. Andrology. Obstetrics Health risk assessment Humans Insulin-Like Growth Factor Binding Protein 3 - blood Insulin-Like Growth Factor I - analysis Insulin-Like Growth Factor II - analysis Male Male genital diseases Males Medical sciences Middle Aged Odds Ratio Physicians Prospective Studies Prostate Prostate cancer Prostate-Specific Antigen - blood Prostatic Neoplasms - etiology Reference Groups Reference Values Regression (Statistics) Regression Analysis Risk Risk Factors Scientific Concepts Statistical Significance Tumors
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