Assessment of Anticollagenase Treatments After Insertion of a Keratoprosthetic Material in the Rabbit Cornea

PURPOSEThis study was performed to evaluate the enzyme production in response to implantation of the hydrogel material used in the experimental Chirila keratoprosthesis (KPro) and to assess the effects of five topical drugs on enzyme production and activity. KPros may be extruded from the cornea as...

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Veröffentlicht in:	Cornea 1998-01, Vol.17 (1), p.108-108
Hauptverfasser:	Fitton, J Helen, Ziegelaar, Brian W, Hicks, Celia R, Clayton, Anthony B, Crawford, Geoffrey J, Constable, Ian J, Chirila, Traian V
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcysteine - administration & dosage Acetylcysteine - pharmacology Administration, Topical Animals Blotting, Western Citrates - administration & dosage Citrates - pharmacology Collagenases - metabolism Cornea - drug effects Cornea - enzymology Cornea - surgery Disease Models, Animal Electrophoresis, Polyacrylamide Gel Gelatinases - metabolism Graft Survival Implants, Experimental Matrix Metalloproteinase Inhibitors Medroxyprogesterone - administration & dosage Medroxyprogesterone - pharmacology Methacrylates Ophthalmic Solutions Prednisolone - administration & dosage Prednisolone - pharmacology Rabbits Tetracycline - administration & dosage Tetracycline - pharmacology Treatment Outcome
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