GTP Hydrolysis Is Essential for Protein Import into the Mitochondrial Matrix

Protein import into the innermost compartment of mitochondria (the matrix) requires a membrane potential (ΔΨ) across the inner membrane, as well as ATP-dependent interactions with chaperones in the matrix and cytosol. The role of nucleoside triphosphates other than ATP during import into the matrix,...

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Veröffentlicht in:	The Journal of biological chemistry 1998-01, Vol.273 (3), p.1420-1424
Hauptverfasser:	Sepuri, Naresh Babu V., Schülke, Norbert, Pain, Debkumar
Format:	Artikel
Sprache:	eng
Schlagworte:	1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE Adenosine Triphosphate - metabolism ALCOHOL DEHYDROGENASE ALCOHOL DESHIDROGENASA ALCOHOL OXIDOREDUCTASES ALCOOL DESHYDROGENASE ATP Biological Transport CELL MEMBRANES Cytosol - metabolism ENZYME PRECURSORS Escherichia coli GUANOSINE TRIPHOSPHATE Guanosine Triphosphate - metabolism HIDROLISIS HYDROLYSE HYDROLYSIS Intracellular Membranes - metabolism Kinetics MEMBRANAS CELULARES MEMBRANE CELLULAIRE Membrane Potentials METABOLISME DES PROTEINES METABOLISMO PROTEICO MITOCHONDRIA Mitochondria - metabolism MITOCHONDRIE MITOCONDRIA NUCLEOTIDE NUCLEOTIDES NUCLEOTIDOS Oxidoreductases Acting on CH-NH Group Donors - metabolism PRECURSEUR D'ENZYME PRECURSORES DE ENZIMAS PROTEIN METABOLISM PROTEIN TRANSPORT SACCHAROMYCES CEREVISIAE
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