Spaceflight Downregulates Antioxidant Defense Systems in Rat Liver

Liver antioxidant enzyme activities, mRNA abundance, and glutathione (GSH) status were investigated in male Sprague-Dawley rats placed in an enclosure module aboard Space Shuttle STS-63 for 8 d (F, n = 6). F animals were compared to rats housed in an enclosure module on the ground (G, n = 9), which...

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Veröffentlicht in:	Free radical biology & medicine 1998-01, Vol.24 (2), p.385-390
Hauptverfasser:	Hollander, J., Gore, M., Fiebig, R., Mazzeo, R., Ohishi, S., Ohno, H., Ji, L.L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidant enzyme Antioxidants - metabolism Catalase - genetics Catalase - metabolism gamma-Glutamyltransferase - metabolism Glutathione Glutathione - metabolism Glutathione Disulfide - metabolism Glutathione Reductase - metabolism Glutathione Transferase - metabolism Lipid peroxidation Liver Liver - metabolism Male Malondialdehyde - metabolism Rat Rats Rats, Sprague-Dawley RNA, Messenger - metabolism Space Flight Space life sciences Spaceflight Superoxide Dismutase - genetics Superoxide Dismutase - metabolism
Online-Zugang:	Volltext
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