Orthotopic heart transplantation for complex congenital heart disease
Orthotopic heart transplantation has become standard therapy for end-stage cardiomyopathy in children and adults, but there has been much less experience with transplantation for complex congenital heart disease. In this report experience with orthotopic transplantation in seven children with variou...
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| Veröffentlicht in: | The Journal of thoracic and cardiovascular surgery 1990-03, Vol.99 (3), p.484-492 |
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| container_end_page | 492 |
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| container_issue | 3 |
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| container_title | The Journal of thoracic and cardiovascular surgery |
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| creator | Mayer, JE, Jr Perry, S O'Brien, P Perez-Atayde, A Jonas, RA Castaneda, AR Parness, IA |
| description | Orthotopic heart transplantation has become standard therapy for end-stage cardiomyopathy in children and adults, but there has been much less experience with transplantation for complex congenital heart disease. In this report experience with orthotopic transplantation in seven children with various forms of complex congenital heart disease is reviewed. Diagnoses included hypoplastic left heart syndrome in two (after stage I palliation), left ventricular diverticulum in one, single ventricle in two (dextrocardia, atrial situs inversus, and total anomalous pulmonary venous return in one patient and post-Fontan repair in the second), D-transposition of the great arteries and ventricular septal defect (post-Senning repair and ventricular septal defect closure) in one, and Ebstein's anomaly with biventricular dysplasia in one. Six of the seven were hospital survivors and there has been one late death at 2 1/3 years. Modifications of the standard operative technique to fit the anatomic variations in these defects are reviewed. |
| doi_str_mv | 10.1016/s0022-5223(19)36979-x |
| format | Article |
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In this report experience with orthotopic transplantation in seven children with various forms of complex congenital heart disease is reviewed. Diagnoses included hypoplastic left heart syndrome in two (after stage I palliation), left ventricular diverticulum in one, single ventricle in two (dextrocardia, atrial situs inversus, and total anomalous pulmonary venous return in one patient and post-Fontan repair in the second), D-transposition of the great arteries and ventricular septal defect (post-Senning repair and ventricular septal defect closure) in one, and Ebstein's anomaly with biventricular dysplasia in one. Six of the seven were hospital survivors and there has been one late death at 2 1/3 years. Modifications of the standard operative technique to fit the anatomic variations in these defects are reviewed.</description><subject>Adolescent</subject><subject>Biopsy</subject><subject>Blood Pressure</subject><subject>Cardiac Output</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Cyclosporins - administration & dosage</subject><subject>Electrocardiography</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Graft Rejection</subject><subject>Heart Defects, Congenital - surgery</subject><subject>Heart Transplantation - methods</subject><subject>Humans</subject><subject>Infant</subject><subject>Male</subject><subject>Myocardium - pathology</subject><issn>0022-5223</issn><issn>1097-685X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkEtLAzEUhYMotVZ_QqEr0cXoTTLJJEsp9QGFLlToLmSSTDtlXiYp1n_v1Ja6Opvvnnv4EBpjeMCA-WMAICRhhNA7LO8pl5lMdmdoiEFmCRdseY6GJ-QSXYWwAYAMsBygAaEgKOdDNFv4uG5j25Vmsnbax0n0ugldpZuoY9k2k6L1E9PWXeV2fTYr15RRV0fYlsHp4K7RRaGr4G6OOUKfz7OP6WsyX7y8TZ_miaGUxcTinOXEiVxzAEsNOImZFGBBCJFacFjazFpIiQBjCJbcSkKYljorgHFOR-j20Nv59mvrQlR1GYyr-rWu3QaVSc4IJ9CD7AAa34bgXaE6X9ba_ygMaq9Pve_dqL0bhaX606eW_d34-GCb186ero6-_gesy9X6u_ROhVpXVU9jtYkmyL5KpSKlv4dyeSY</recordid><startdate>19900301</startdate><enddate>19900301</enddate><creator>Mayer, JE, Jr</creator><creator>Perry, S</creator><creator>O'Brien, P</creator><creator>Perez-Atayde, A</creator><creator>Jonas, RA</creator><creator>Castaneda, AR</creator><creator>Parness, IA</creator><general>AATS/WTSA</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19900301</creationdate><title>Orthotopic heart transplantation for complex congenital heart disease</title><author>Mayer, JE, Jr ; Perry, S ; O'Brien, P ; Perez-Atayde, A ; Jonas, RA ; Castaneda, AR ; Parness, IA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c335t-d1b5b2e8ba600d3c0e915980d08884d0e19d7dd04280cc2196d9225a9a7f05663</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Adolescent</topic><topic>Biopsy</topic><topic>Blood Pressure</topic><topic>Cardiac Output</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Cyclosporins - administration & dosage</topic><topic>Electrocardiography</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Graft Rejection</topic><topic>Heart Defects, Congenital - surgery</topic><topic>Heart Transplantation - methods</topic><topic>Humans</topic><topic>Infant</topic><topic>Male</topic><topic>Myocardium - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mayer, JE, Jr</creatorcontrib><creatorcontrib>Perry, S</creatorcontrib><creatorcontrib>O'Brien, P</creatorcontrib><creatorcontrib>Perez-Atayde, A</creatorcontrib><creatorcontrib>Jonas, RA</creatorcontrib><creatorcontrib>Castaneda, AR</creatorcontrib><creatorcontrib>Parness, IA</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of thoracic and cardiovascular surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mayer, JE, Jr</au><au>Perry, S</au><au>O'Brien, P</au><au>Perez-Atayde, A</au><au>Jonas, RA</au><au>Castaneda, AR</au><au>Parness, IA</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Orthotopic heart transplantation for complex congenital heart disease</atitle><jtitle>The Journal of thoracic and cardiovascular surgery</jtitle><addtitle>J Thorac Cardiovasc Surg</addtitle><date>1990-03-01</date><risdate>1990</risdate><volume>99</volume><issue>3</issue><spage>484</spage><epage>492</epage><pages>484-492</pages><issn>0022-5223</issn><eissn>1097-685X</eissn><abstract>Orthotopic heart transplantation has become standard therapy for end-stage cardiomyopathy in children and adults, but there has been much less experience with transplantation for complex congenital heart disease. 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| ispartof | The Journal of thoracic and cardiovascular surgery, 1990-03, Vol.99 (3), p.484-492 |
| issn | 0022-5223 1097-685X |
| language | eng |
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| source | MEDLINE; Access via ScienceDirect (Elsevier); EZB-FREE-00999 freely available EZB journals |
| subjects | Adolescent Biopsy Blood Pressure Cardiac Output Child Child, Preschool Cyclosporins - administration & dosage Electrocardiography Female Follow-Up Studies Graft Rejection Heart Defects, Congenital - surgery Heart Transplantation - methods Humans Infant Male Myocardium - pathology |
| title | Orthotopic heart transplantation for complex congenital heart disease |
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