Ras-dependent apoptosis correlates with persistent activation of stress-activated protein kinases and induction of isoform(s) of Bcl-x

Ras proteins are signal transducers for many cellular responses. However, it is not well established whether Ras-signaling also contributes to apoptosis. We have constructed H-RasR12-transformed Rat1 fibroblasts using tetracycline operator/repressor (TetO/TetR)-based conditional vectors. Rat1/TetO-R...

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Veröffentlicht in:	Cell death and differentiation 1997-12, Vol.4 (8), p.745-755
Hauptverfasser:	Yu, K, Chen, Y N, Ravera, C P, Bayona, W, Nalin, C M, Mallon, R
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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