Validity of a two-point acetaminophen pharmacokinetic study

The pharmacokinetics of a single 650-mg intravenous dose of acetaminophen were determined in 82 volunteers using multiple (13 or more) plasma acetaminophen concentrations measured by high pressure liquid chromatography during 24 h after dosage. Kinetic values from the complete study were compared wi...

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Veröffentlicht in:Therapeutic drug monitoring 1990, Vol.12 (1), p.35-39
Hauptverfasser: SCAVONE, J. M, GREENBLATT, D. J, BLYDEN, G. T, LUNA, B. G, HARMATZ, J. S
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Sprache:eng
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