The effects of foreign transmembrane domains on the biosynthesis of the influenza virus hemagglutinin

Eleven chimeric proteins were created in which the transmembrane, the cytoplasmic, or both topological domains of the influenza virus hemagglutinin (HA) were replaced with those from five other glycoproteins. All of the chimeric HAs reached the cell surface but appeared to differ in the degree to wh...

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Veröffentlicht in:The Journal of biological chemistry 1990-03, Vol.265 (8), p.4760-4767
Hauptverfasser: Lazarovits, J, Shia, S P, Ktistakis, N, Lee, M S, Bird, C, Roth, M G
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Sprache:eng
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