Mycobacterium tuberculosis aerogenic rechallenge infections in B cell-deficient mice

Objective: Use gene disrupted mice to examine the possible role of secretory antibody on resistance to re-exposure to pulmonary tuberculosis. Design: Mice deficient in B cells due to targeted gene disruption were infected by aerosol exposure with Mycobacterium tuberculosis. A further set were identi...

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Veröffentlicht in:	Tubercle and lung disease 1997, Vol.78 (5), p.257-261
Hauptverfasser:	Johnson, C.M., Cooper, A.M., Frank, A.A., Bonorino, C.B.C., Wysoki, L.J., Orme, I.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aerosols Animals B-Lymphocytes - immunology Female Gene Expression Immune Tolerance Immunologic Memory Interferon-gamma - biosynthesis Interferon-gamma - genetics Lung - immunology Lung - microbiology Male Mice Mice, Inbred C57BL RNA, Messenger - genetics Tuberculosis, Pulmonary - immunology Tuberculosis, Pulmonary - microbiology
Online-Zugang:	Volltext
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