Oxidation of glycerol to formaldehyde by rat liver microsomes: Effects of cytochrome P-450 inducing agents

Glycerol was shown recently to be metabolized to formaldehyde by microsomes from chowfed control rats (Winters et al., Biochem Biophys Res Commun 153: 612–617, 1988). In the present study, experiments were carried out to evaluate the oxidation of glycerol by microsomes isolated from rats treated wit...

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Veröffentlicht in:	Biochemical pharmacology 1990-02, Vol.39 (4), p.697-705
Hauptverfasser:	Winters, Debra K., Cederbaum, Arthur I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetone - pharmacology Aldehyde Oxidoreductases - metabolism Animals Biological and medical sciences Carbon Monoxide - pharmacology Cell metabolism, cell oxidation Cell physiology Cytochrome P-450 Enzyme System - metabolism Enzyme Induction - drug effects Ethanol - pharmacology Fomepizole Formaldehyde - metabolism Fundamental and applied biological sciences. Psychology Glycerol - metabolism Isoenzymes - metabolism Kinetics Male Methylcholanthrene - pharmacology Microsomes, Liver - drug effects Microsomes, Liver - metabolism Molecular and cellular biology NAD - metabolism Oxidation-Reduction Phenobarbital - pharmacology Pyrazoles - pharmacology Rats Rats, Inbred Strains
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