Renin Production by Nephroblastoma Cells in Culture

Nephroblastoma cells have been cultured for 19 days. During this time cell growth and active and inactive renin secretion were monitored. Inactive renin was found to be secreted in excess of active renin. The main secretory protein, precipitated with antirenin IgG was found to have a molecular mass...

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Veröffentlicht in:	American journal of hypertension 1990-02, Vol.3 (2), p.148-150
Hauptverfasser:	Inglis, G. C., Leckie, B. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Division Humans Kidney Neoplasms - enzymology Kidney Neoplasms - metabolism Kidney Neoplasms - pathology Molecular Weight Renin - analysis Renin - biosynthesis Renin - metabolism Tumor Cells, Cultured - enzymology Tumor Cells, Cultured - metabolism Tumor Cells, Cultured - pathology Wilms Tumor - enzymology Wilms Tumor - metabolism Wilms Tumor - pathology
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Beschreibung
Zusammenfassung:	Nephroblastoma cells have been cultured for 19 days. During this time cell growth and active and inactive renin secretion were monitored. Inactive renin was found to be secreted in excess of active renin. The main secretory protein, precipitated with antirenin IgG was found to have a molecular mass of 52,000 daltons. Am J Hypertens 1990;3:148-150
ISSN:	0895-7061 1941-7225
DOI:	10.1093/ajh/3.2.148