Ligand‐dependent release of active neutrophil collagenase

The amount of active neutrophil (PMN) collagenase released extracellularly is dependent on the PMN‐activating ligand. Neutrophils stimulated with soluble ligands, including FMLP, platelet‐activating factor, or heat‐aggregated IgG, released very little active collagenase, in contrast to cells stimula...

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Veröffentlicht in:	Arthritis and rheumatism 1990-02, Vol.33 (2), p.228-234
Hauptverfasser:	Chatham, W. Winn, Heck, Louis W., Blackburn, Warren D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Arthritis, Rheumatoid - enzymology Biological and medical sciences Cartilage, Articular - enzymology Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Immunobiology Immunoglobulin G - physiology In Vitro Techniques Ligands Microbial Collagenase - blood Myeloid cells: ontogeny, maturation, markers, receptors N-Formylmethionine Leucyl-Phenylalanine - pharmacology Neutrophils - drug effects Neutrophils - enzymology Platelet Activating Factor - pharmacology Radioimmunoassay Zymosan - pharmacology
Online-Zugang:	Volltext
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