Chronic Ethanol Administration Decreases Phosphorylation of Cyclic AMP Response Element‐Binding Protein in Granule Cells of Rat Cerebellum

: To help define the molecular basis of ethanol's actions on the nervous system, we have in previous studies demonstrated that ethanol administration triggers a robust increase in cyclic AMP‐response element‐binding protein (CREB) phosphorylation in the cerebellum. The purpose of the present st...

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Veröffentlicht in:	Journal of neurochemistry 1998-01, Vol.70 (1), p.224-232
Hauptverfasser:	Yang, Xiaoju, Horn, Kristin, Baraban, Jay M., Wand, Gary S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Alcoholism and acute alcohol poisoning Animals Biological and medical sciences Calcium-Calmodulin-Dependent Protein Kinase Type 4 Calcium-Calmodulin-Dependent Protein Kinases - metabolism Catalysis Cerebellum Cerebellum - cytology Cerebellum - drug effects Cerebellum - metabolism Cyclic AMP Response Element-Binding Protein - metabolism Cyclic AMP-Dependent Protein Kinases - metabolism Cyclic AMP‐response element binding protein Ethanol - pharmacology Male Medical sciences Neurons - drug effects Neurons - metabolism Phosphorylation Phosphorylation - drug effects Rats Rats, Sprague-Dawley Time Factors Toxicology
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