Pharmacokinetics and Pharmacodynamics of Famotidine in Infants

The pharmacokinetics and pharmacodynamics of intravenous famotidine were evaluated in 10 infants ranging from 5 to 19 days of age who had a therapeutic indication for the prophylactic treatment of stress ulceration. After a 0.5‐mg/kg infusion of famotidine, timed serum (n = 6), urine (24‐hour collec...

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Veröffentlicht in:	Journal of clinical pharmacology 1998-12, Vol.38 (12), p.1089-1095
Hauptverfasser:	James, Laura P., Marotti, Tonya, Stowe, Cindy D., Farrar, Henry C., Taylor, Bonnie J., Kearns, Gregory L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Digestive system Famotidine - pharmacokinetics Famotidine - pharmacology Female Gastric Acidity Determination Histamine H2 Antagonists - pharmacokinetics Humans Infant Infant, Newborn Male Medical sciences Metabolic Clearance Rate Pharmacology. Drug treatments
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