A novel BRCA1 mutation in an identical twin pair with similar clinical histories

Factors affecting the penetrance and expression of BRCA1 are not understood. Breast cancer risk and ovarian cancer risk, in general, are known to be associated with non-Mendelian factors. However, whether and how these various factors influence tumor development in BRCA1 mutation carriers is not kno...

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Veröffentlicht in:	Cancer genetics and cytogenetics 1998, Vol.100 (1), p.43-48
Hauptverfasser:	Miesfeldt, Susan, Turner, Beverely L, Lovell, Mark A, Cooper, Michael R, Lescallett, Jennifer, Jones, Susan M
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Birth control Breast Neoplasms - genetics Diseases in Twins Female Genes, BRCA1 Gynecology. Andrology. Obstetrics Humans Medical sciences Middle Aged Mutation Other methods of contraception. Sterilization Ovarian Neoplasms - genetics Twins, Monozygotic
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