Cloning: New breakthroughs leading to commercial opportunities

Research on cloning animals, again, came to the forefront of public attention in 1997. Most scientists involved in biomedical and agricultural research have emphasized the benefits, of which there are many, of cloning to the public. Basic studies on nuclear transfer have and will continue to contrib...

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Veröffentlicht in:Theriogenology 1998, Vol.49 (1), p.129-138
Hauptverfasser: Stice, S.L., Robl, J.M., de Leon, F.A.Ponce, Jerry, J., Golueke, P.G., Cibelli, J.B., Kane, J.J.
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container_end_page 138
container_issue 1
container_start_page 129
container_title Theriogenology
container_volume 49
creator Stice, S.L.
Robl, J.M.
de Leon, F.A.Ponce
Jerry, J.
Golueke, P.G.
Cibelli, J.B.
Kane, J.J.
description Research on cloning animals, again, came to the forefront of public attention in 1997. Most scientists involved in biomedical and agricultural research have emphasized the benefits, of which there are many, of cloning to the public. Basic studies on nuclear transfer have and will continue to contribute to our understanding of how genomic activation and cell cycle synchrony affect nuclear reprogramming and cloning efficiencies, specifically. Also, more basic information on actual mechanisms and specific factors in the oocyte causing nuclear reprogramming is forthcoming. As new molecular approaches in functional genomics are combined with nuclear transfer experiments, new genes involved in nuclear reprogramming will be found. The commercial potentials of products stemming from discoveries in cloning are vast. Cloning will be a more efficient, faster and more useful way of making transgenic fetuses for cell therapies, adult animals for protein production and organs for xenotransplantation. Clearly there are new opportunities in animal cloning technology that will produce many benefits to society.
doi_str_mv 10.1016/S0093-691X(97)00407-X
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subjects Animals
Animals, Genetically Modified
Cell Cycle
Cell Nucleus - ultrastructure
cloning
Cloning, Organism - methods
Cloning, Organism - veterinary
Mammals
nuclear reprogramming
nuclear transfer
Nuclear Transfer Techniques
transgenics
title Cloning: New breakthroughs leading to commercial opportunities
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