High-Density Functional Gastrin Releasing Peptide Receptors on Primate Cells

Gastrin releasing peptide (GRP) is a 27 amino acid hormone that elicits a variety of biological effects. Receptor-binding antagonists of GRP may have therapeutic use in several pathologic conditions including cancer. The identification and characterization of GRP receptor antagonists have been aided...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 1990-03, Vol.82 (5), p.402-407
Hauptverfasser:	Heimbrook, David C., Wallen, John W., Balishin, Nancy L., Friedman, Arthur, Oliff, Allen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding, Competitive Biological and medical sciences Calcium - metabolism Cell Line Cos-7 cells Cross-Linking Reagents - pharmacology Gastrin-Releasing Peptide Haplorhini Medical sciences Mitogens Peptides - metabolism Peptides - pharmacology Receptors, Bombesin Receptors, Neurotransmitter - drug effects Receptors, Neurotransmitter - metabolism Tumors
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