Measurement of cortisol and lymphocyte subpopulations in depressed and conduct-disordered adolescents
Lymphocyte subpopulations were analyzed in 11 adolescents with major depressive disorder, 11 with conduct disorder, and eight normal age-matched subjects. No significant differences were Noted on any T or B cell measure between the groups. Further, no significant correlations were found between any...
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| Veröffentlicht in: | Journal of affective disorders 1990-02, Vol.18 (2), p.91-96 |
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| container_end_page | 96 |
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| container_start_page | 91 |
| container_title | Journal of affective disorders |
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| creator | Targum, Steven D. Clarkson, Lindsay L. Magac-Harris, Kelly Marshall, Lois E. Skwerer, Robert G. |
| description | Lymphocyte subpopulations were analyzed in 11 adolescents with major depressive disorder, 11 with conduct disorder, and eight normal age-matched subjects. No significant differences were Noted on any T or B cell measure between the groups. Further, no significant correlations were found between any cortisol measure (baseline cortisol, post-dexamethasone cortisol, urinary free cortisol) and any lymphocyte measure in either depressed or conduct-disordered adolescents. The negative findings in this small sample contrast with those reported in adult patients and suggest that an aging effect may be associated with the immunological changes reported in older depressed patients. |
| doi_str_mv | 10.1016/0165-0327(90)90064-F |
| format | Article |
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No significant differences were Noted on any T or B cell measure between the groups. Further, no significant correlations were found between any cortisol measure (baseline cortisol, post-dexamethasone cortisol, urinary free cortisol) and any lymphocyte measure in either depressed or conduct-disordered adolescents. The negative findings in this small sample contrast with those reported in adult patients and suggest that an aging effect may be associated with the immunological changes reported in older depressed patients.</description><identifier>ISSN: 0165-0327</identifier><identifier>EISSN: 1573-2517</identifier><identifier>DOI: 10.1016/0165-0327(90)90064-F</identifier><identifier>PMID: 2137474</identifier><identifier>CODEN: JADID7</identifier><language>eng</language><publisher>Amsterdam: Elsevier B.V</publisher><subject>Adolescent ; Adolescents ; B-Lymphocytes - immunology ; Biological and medical sciences ; Child Behavior Disorders - diagnosis ; Child Behavior Disorders - immunology ; Cortisol ; Depressive Disorder - diagnosis ; Depressive Disorder - immunology ; Dexamethasone ; Female ; Humans ; Hydrocortisone - blood ; Leukocyte Count ; Lymphocytes ; Major depressive disorder ; Male ; Medical sciences ; Miscellaneous ; Personality Tests ; Psychology. Psychoanalysis. 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Psychiatry ; T-Lymphocytes - immunology ; Techniques and methods</subject><ispartof>Journal of affective disorders, 1990-02, Vol.18 (2), p.91-96</ispartof><rights>1990</rights><rights>1990 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c386t-5cfd02b0b82733e887e661e6c6c1ea3d4a203148af20bdeefd09ded0b05e14aa3</citedby><cites>FETCH-LOGICAL-c386t-5cfd02b0b82733e887e661e6c6c1ea3d4a203148af20bdeefd09ded0b05e14aa3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/016503279090064F$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,65309</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=6694735$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2137474$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Targum, Steven D.</creatorcontrib><creatorcontrib>Clarkson, Lindsay L.</creatorcontrib><creatorcontrib>Magac-Harris, Kelly</creatorcontrib><creatorcontrib>Marshall, Lois E.</creatorcontrib><creatorcontrib>Skwerer, Robert G.</creatorcontrib><title>Measurement of cortisol and lymphocyte subpopulations in depressed and conduct-disordered adolescents</title><title>Journal of affective disorders</title><addtitle>J Affect Disord</addtitle><description>Lymphocyte subpopulations were analyzed in 11 adolescents with major depressive disorder, 11 with conduct disorder, and eight normal age-matched subjects. No significant differences were Noted on any T or B cell measure between the groups. Further, no significant correlations were found between any cortisol measure (baseline cortisol, post-dexamethasone cortisol, urinary free cortisol) and any lymphocyte measure in either depressed or conduct-disordered adolescents. The negative findings in this small sample contrast with those reported in adult patients and suggest that an aging effect may be associated with the immunological changes reported in older depressed patients.</description><subject>Adolescent</subject><subject>Adolescents</subject><subject>B-Lymphocytes - immunology</subject><subject>Biological and medical sciences</subject><subject>Child Behavior Disorders - diagnosis</subject><subject>Child Behavior Disorders - immunology</subject><subject>Cortisol</subject><subject>Depressive Disorder - diagnosis</subject><subject>Depressive Disorder - immunology</subject><subject>Dexamethasone</subject><subject>Female</subject><subject>Humans</subject><subject>Hydrocortisone - blood</subject><subject>Leukocyte Count</subject><subject>Lymphocytes</subject><subject>Major depressive disorder</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Miscellaneous</subject><subject>Personality Tests</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>T-Lymphocytes - immunology</subject><subject>Techniques and methods</subject><issn>0165-0327</issn><issn>1573-2517</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEFL5DAUx4O4jKPrN1DoQUQP3U2aNmkugoijC7PsRc8hTV4x0jY1r12Yb2_GGeboITzI-_3_PH6EXDD6i1EmfqdX5ZQX8kbRW0WpKPPVEVmySvK8qJg8JssDckJOEd9pgpSkC7IoGJelLJcE_oLBOUIPw5SFNrMhTh5Dl5nBZd2mH9-C3UyQ4dyMYZw7M_kwYOaHzMEYARHcF2rD4GY75S6Fo4O4_XahA7SpGH-SH63pEM7384y8rh5fHp7z9b-nPw_369zyWkx5ZVtHi4Y2dSE5h7qWIAQDYYVlYLgrTUE5K2vTFrRxAIlWDhxtaAWsNIafketd7xjDxww46d6nC7rODBBm1FIJpgqhEljuQBsDYoRWj9H3Jm40o3prV2_V6a06raj-sqtXKXa575-bHtwhtNeZ9lf7vUFrujaawXo8YEKoUvIqYXc7DJKL_x6iRuthsOB8BDtpF_z3d3wCaPWY4A</recordid><startdate>19900201</startdate><enddate>19900201</enddate><creator>Targum, Steven D.</creator><creator>Clarkson, Lindsay L.</creator><creator>Magac-Harris, Kelly</creator><creator>Marshall, Lois E.</creator><creator>Skwerer, Robert G.</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19900201</creationdate><title>Measurement of cortisol and lymphocyte subpopulations in depressed and conduct-disordered adolescents</title><author>Targum, Steven D. ; Clarkson, Lindsay L. ; Magac-Harris, Kelly ; Marshall, Lois E. ; Skwerer, Robert G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-5cfd02b0b82733e887e661e6c6c1ea3d4a203148af20bdeefd09ded0b05e14aa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Adolescent</topic><topic>Adolescents</topic><topic>B-Lymphocytes - immunology</topic><topic>Biological and medical sciences</topic><topic>Child Behavior Disorders - diagnosis</topic><topic>Child Behavior Disorders - immunology</topic><topic>Cortisol</topic><topic>Depressive Disorder - diagnosis</topic><topic>Depressive Disorder - immunology</topic><topic>Dexamethasone</topic><topic>Female</topic><topic>Humans</topic><topic>Hydrocortisone - blood</topic><topic>Leukocyte Count</topic><topic>Lymphocytes</topic><topic>Major depressive disorder</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Miscellaneous</topic><topic>Personality Tests</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>T-Lymphocytes - immunology</topic><topic>Techniques and methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Targum, Steven D.</creatorcontrib><creatorcontrib>Clarkson, Lindsay L.</creatorcontrib><creatorcontrib>Magac-Harris, Kelly</creatorcontrib><creatorcontrib>Marshall, Lois E.</creatorcontrib><creatorcontrib>Skwerer, Robert G.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of affective disorders</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Targum, Steven D.</au><au>Clarkson, Lindsay L.</au><au>Magac-Harris, Kelly</au><au>Marshall, Lois E.</au><au>Skwerer, Robert G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Measurement of cortisol and lymphocyte subpopulations in depressed and conduct-disordered adolescents</atitle><jtitle>Journal of affective disorders</jtitle><addtitle>J Affect Disord</addtitle><date>1990-02-01</date><risdate>1990</risdate><volume>18</volume><issue>2</issue><spage>91</spage><epage>96</epage><pages>91-96</pages><issn>0165-0327</issn><eissn>1573-2517</eissn><coden>JADID7</coden><abstract>Lymphocyte subpopulations were analyzed in 11 adolescents with major depressive disorder, 11 with conduct disorder, and eight normal age-matched subjects. No significant differences were Noted on any T or B cell measure between the groups. Further, no significant correlations were found between any cortisol measure (baseline cortisol, post-dexamethasone cortisol, urinary free cortisol) and any lymphocyte measure in either depressed or conduct-disordered adolescents. The negative findings in this small sample contrast with those reported in adult patients and suggest that an aging effect may be associated with the immunological changes reported in older depressed patients.</abstract><cop>Amsterdam</cop><pub>Elsevier B.V</pub><pmid>2137474</pmid><doi>10.1016/0165-0327(90)90064-F</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0165-0327 |
| ispartof | Journal of affective disorders, 1990-02, Vol.18 (2), p.91-96 |
| issn | 0165-0327 1573-2517 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adolescent Adolescents B-Lymphocytes - immunology Biological and medical sciences Child Behavior Disorders - diagnosis Child Behavior Disorders - immunology Cortisol Depressive Disorder - diagnosis Depressive Disorder - immunology Dexamethasone Female Humans Hydrocortisone - blood Leukocyte Count Lymphocytes Major depressive disorder Male Medical sciences Miscellaneous Personality Tests Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry T-Lymphocytes - immunology Techniques and methods |
| title | Measurement of cortisol and lymphocyte subpopulations in depressed and conduct-disordered adolescents |
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