A novel peptide which stimulates adenylate cyclase: Molecular cloning and characterization of the ovine and human cDNAs

A novel neuropeptide which remarkably stimulates adenylate cyclase in rat anterior pituitary cell cultures has been recently isolated from ovine hypothalami by A. Arimura and his collaborators ( Biochem. Biophys. Res. Commun. 164, 567–574(1989)). This peptide was designated as PACAP3(( Pituitary Ade...

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Veröffentlicht in:	Biochemical and biophysical research communications 1990-01, Vol.166 (1), p.81-89
Hauptverfasser:	Kimura, Chiharu, Ohkubo, Shoichi, Ogi, Kazuhiro, Hosoya, Masaki, Itoh, Yasuaki, Onda, Haruo, Miyata, Atsuro, Jiang, Lun, Dahl, Raymond R., Stibbs, Henry H., Arimura, Akira, Fujino, Masahiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenylyl Cyclases - metabolism Amino Acid Sequence Analytical, structural and metabolic biochemistry Animals Base Sequence Biological and medical sciences Blotting, Southern Cloning, Molecular DNA - genetics Enzyme Activation Enzymes and enzyme inhibitors Fundamental and applied biological sciences. Psychology genes Humans Hypothalamus - metabolism Lyases Molecular Sequence Data Neuropeptides - genetics Neuropeptides - physiology Oligonucleotide Probes Pituitary Adenylate Cyclase-Activating Polypeptide Pituitary Gland, Anterior - metabolism Protein Conformation Protein Precursors - genetics Restriction Mapping Sequence Homology, Nucleic Acid Sheep
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