Effects of Redox-Related Congeners of NO on Apoptosis and Caspase-3 Activity

Nitric oxide has been shown to inhibit apoptosis of human umbilical venous endothelial cells (HUVEC). Therefore we investigated the effect of different NO donors, PAPA NONOate (NOC-15; NO•) and nitrosodium tetrafluoroborate (NOBF4, NO+), and the reaction product of NO and O2−, peroxynitrite (ONOO−),...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nitric oxide 1997-08, Vol.1 (4), p.282-293
Hauptverfasser:	Haendeler, Judith, Weiland, Ulrike, Zeiher, Andreas M., Dimmeler, Stefanie
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis - physiology Caspase 3 Caspases Cells, Cultured Cysteine Endopeptidases - metabolism Cysteine Proteinase Inhibitors DNA fragmentation Endothelium, Vascular - cytology Endothelium, Vascular - enzymology Humans Nitric Oxide - chemistry Nitric Oxide - physiology Oxidation-Reduction peroxynitrite proteases Recombinant Proteins - metabolism S-nitrosylation TNF-α Tumor Necrosis Factor-alpha - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!