Seizures, memory and synaptic plasticity

Electrophysiological studies of the rodent hippocampus show that repeated seizure activity has a profound, deleterious effect on an important form of synaptic plasticity (long-term potentiation, LTP) which has been suggested to underlie memory formation. It appears that seizure activity incrementall...

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Veröffentlicht in:	Seizure (London, England) England), 1997-10, Vol.6 (5), p.351-359
Hauptverfasser:	Reid, Ian C., Stewart, Caroline A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals electroconvulsive therapy Electroconvulsive Therapy - adverse effects epilepsy Epilepsy - physiopathology hippocampus Hippocampus - physiopathology Humans ketamine learning Learning Disorders - etiology Learning Disorders - physiopathology Learning Disorders - prevention & control long-term potentiation Long-Term Potentiation - physiology Memory Disorders - etiology Memory Disorders - physiopathology Memory Disorders - prevention & control Mood Disorders - therapy Rats Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors
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