Specific binding of human interleukin-3 and granulocyte-macrophage colony-stimulating factor to human basophils

The human T cell-derived cytokines interleukin (IL)-3 and granulocyte-macrophage colony-stimulating factor (GM-CSF) were examined for their ability to bind to human basophils. Basophils were obtained from the peripheral blood of a patient with chronic myeloid leukemia undergoing basophilic different...

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Veröffentlicht in:	Journal of allergy and clinical immunology 1990, Vol.85 (1), p.99-102
Hauptverfasser:	Lopez, A.F., Lyons, A.B., Eglinton, J.M., Park, L.S., To, L.B., Clark, S.C., Vadas, M.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Basophils - metabolism Biological and medical sciences Colony-Stimulating Factors - analysis Colony-Stimulating Factors - metabolism Fundamental and applied biological sciences. Psychology Fundamental immunology Granulocyte-Macrophage Colony-Stimulating Factor Growth Substances - analysis Growth Substances - metabolism Humans Immunobiology Interleukin-3 - analysis Interleukin-3 - metabolism Leukemia, Myelogenous, Chronic, BCR-ABL Positive - blood Myeloid cells: ontogeny, maturation, markers, receptors Protein Binding - physiology Radioligand Assay Receptors, Cell Surface - analysis Receptors, Cell Surface - metabolism Receptors, Granulocyte Colony-Stimulating Factor Receptors, Immunologic - analysis Receptors, Immunologic - metabolism Receptors, Interleukin-3 Recombinant Proteins - analysis Recombinant Proteins - metabolism
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