A sensitive method for the quantification of fluticasone propionate in human plasma by high-performance liquid chromatography/atmospheric pressure chemical ionisation mass spectrometry

A highly sensitive and selective method has been developed for the quantification of fluticasone propionate (FP) in human plasma. The drug was isolated from human plasma using C 18 solid-phase extraction cartridges. The analysis was based on high-performance liquid chromatography/atmospheric pressur...

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Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 1997-11, Vol.16 (3), p.447-452
Hauptverfasser:	Li, Yuan Nian (Benny), Tattam, Bruce N, Brown, Kenneth F, Seale, John P
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Androstadienes - blood Anti-Inflammatory Agents - blood Atmospheric pressure chemical ionisation mass spectrometry Biological and medical sciences Calibration Chromatography, High Pressure Liquid Fluticasone Fluticasone propionate General pharmacology Humans Mass Spectrometry Medical sciences Pharmacology. Drug treatments Reproducibility of Results Reverse-phase liquid chromatography
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