Clinical experience with routine Gd-DTPA administration for MR imaging of the brain
A retrospective analysis of intracranial magnetic resonance (MR scans of 514 patients who underwent nonselective Gd-DTPA enhanced MR imaging was performed to determine the efficacy of this protocol for Gd-DTPA administration. This report reviews the frequency and clinical significance of abnormally...
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| Veröffentlicht in: | Journal of computer assisted tomography 1990, Vol.14 (1), p.11-17 |
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| container_title | Journal of computer assisted tomography |
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| creator | SCHWAIGHOFER, B. W KLEIN, M. V WESBEY, G HESSELINK, J. R |
| description | A retrospective analysis of intracranial magnetic resonance (MR scans of 514 patients who underwent nonselective Gd-DTPA enhanced MR imaging was performed to determine the efficacy of this protocol for Gd-DTPA administration. This report reviews the frequency and clinical significance of abnormally enhancing areas that were entirely undetectable on precontrast images or would have been missed without the retrospective knowledge of enhancement. Fifty-seven patients (11% of the 514 patients studied) showed enhancing lesions, with 16 (3.1% of the total) of these patients demonstrating one or more lesions identifiable only on postcontrast images. Of those 16 patients, 8 had other focal abnormalities on precontrast studies, whereas the remaining 8 (1.6% of the total) had negative precontrast studies. The new diagnoses affected clinical management directly in five patients and in another nine contributed potentially significant information. Considerations regarding a selective versus nonselective protocol for Gd-DTPA administration for intracranial MR imaging and the use of clinical information to augment these protocols are discussed. |
| doi_str_mv | 10.1097/00004728-199001000-00002 |
| format | Article |
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V</creatorcontrib><creatorcontrib>WESBEY, G</creatorcontrib><creatorcontrib>HESSELINK, J. R</creatorcontrib><title>Clinical experience with routine Gd-DTPA administration for MR imaging of the brain</title><title>Journal of computer assisted tomography</title><addtitle>J Comput Assist Tomogr</addtitle><description>A retrospective analysis of intracranial magnetic resonance (MR scans of 514 patients who underwent nonselective Gd-DTPA enhanced MR imaging was performed to determine the efficacy of this protocol for Gd-DTPA administration. This report reviews the frequency and clinical significance of abnormally enhancing areas that were entirely undetectable on precontrast images or would have been missed without the retrospective knowledge of enhancement. Fifty-seven patients (11% of the 514 patients studied) showed enhancing lesions, with 16 (3.1% of the total) of these patients demonstrating one or more lesions identifiable only on postcontrast images. Of those 16 patients, 8 had other focal abnormalities on precontrast studies, whereas the remaining 8 (1.6% of the total) had negative precontrast studies. The new diagnoses affected clinical management directly in five patients and in another nine contributed potentially significant information. Considerations regarding a selective versus nonselective protocol for Gd-DTPA administration for intracranial MR imaging and the use of clinical information to augment these protocols are discussed.</description><subject>Biological and medical sciences</subject><subject>Brain - pathology</subject><subject>Brain Neoplasms - diagnosis</subject><subject>Contrast Media</subject><subject>Female</subject><subject>Gadolinium</subject><subject>Gadolinium DTPA</subject><subject>Humans</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Nervous system</subject><subject>Organometallic Compounds</subject><subject>Pentetic Acid</subject><subject>Radiodiagnosis. Nmr imagery. 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Nmr spectrometry</topic><topic>Retrospective Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SCHWAIGHOFER, B. W</creatorcontrib><creatorcontrib>KLEIN, M. V</creatorcontrib><creatorcontrib>WESBEY, G</creatorcontrib><creatorcontrib>HESSELINK, J. R</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of computer assisted tomography</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SCHWAIGHOFER, B. W</au><au>KLEIN, M. V</au><au>WESBEY, G</au><au>HESSELINK, J. R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical experience with routine Gd-DTPA administration for MR imaging of the brain</atitle><jtitle>Journal of computer assisted tomography</jtitle><addtitle>J Comput Assist Tomogr</addtitle><date>1990</date><risdate>1990</risdate><volume>14</volume><issue>1</issue><spage>11</spage><epage>17</epage><pages>11-17</pages><issn>0363-8715</issn><eissn>1532-3145</eissn><coden>JCATD5</coden><abstract>A retrospective analysis of intracranial magnetic resonance (MR scans of 514 patients who underwent nonselective Gd-DTPA enhanced MR imaging was performed to determine the efficacy of this protocol for Gd-DTPA administration. This report reviews the frequency and clinical significance of abnormally enhancing areas that were entirely undetectable on precontrast images or would have been missed without the retrospective knowledge of enhancement. 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| ispartof | Journal of computer assisted tomography, 1990, Vol.14 (1), p.11-17 |
| issn | 0363-8715 1532-3145 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Biological and medical sciences Brain - pathology Brain Neoplasms - diagnosis Contrast Media Female Gadolinium Gadolinium DTPA Humans Investigative techniques, diagnostic techniques (general aspects) Magnetic Resonance Imaging Male Medical sciences Middle Aged Nervous system Organometallic Compounds Pentetic Acid Radiodiagnosis. Nmr imagery. Nmr spectrometry Retrospective Studies |
| title | Clinical experience with routine Gd-DTPA administration for MR imaging of the brain |
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