Tropomyosin-troponin complex stabilizes the pointed ends of actin filaments against polymerization and depolymerization

In striated muscle the pointed ends of polar actin filaments are directed toward the center of the sarcomer. Formed filaments keep a constant length of about 1 μm. As polymerization and depolymerization at free pointed ends are not sufficiently slow to account for the constant length of the filament...

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Veröffentlicht in:	FEBS letters 1990-01, Vol.260 (2), p.266-268
Hauptverfasser:	Weigt, Christiane, Schoepper, Beate, Wegner, Albrecht
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Actin Depolymerizing Factors Actins - analysis Analytical, structural and metabolic biochemistry Animals Binding Sites - drug effects Biological and medical sciences Contractile proteins Destrin Fluorescence Fundamental and applied biological sciences. Psychology Holoproteins Microfilament Proteins - antagonists & inhibitors Myofibrils - analysis Polymerization Polymers - analysis Proteins Rabbits Sarcomeres - analysis skeletal muscle Tropomyosin Tropomyosin - pharmacology Troponin Troponin - pharmacology
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