Cellular effects of hypercholesterolemia in modulation of cancer growth and metastasis: a review of the evidence

Hypercholesterolemia and increased cancer risk have been associated, particularly with the high fat diets characteristic of Western societies. We were interested in the possible association between prexisting hypercholesterolemia and the rapidity and extent of tumor metastases in these patients. To...

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Veröffentlicht in:	Surgical Oncology 1997-11, Vol.6 (3), p.179-185
Hauptverfasser:	Mehta, Nikhil, Hordines, John, Volpe, Carmine, Doerr, Ralph, Cohen, Stefan A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals cancer Cholesterol, LDL - adverse effects Dietary Fats - adverse effects Endothelium, Vascular - physiopathology Female Humans hypercholesterolemia Hypercholesterolemia - complications Hypercholesterolemia - metabolism Hypercholesterolemia - pathology LDL lovastatin Male metastasis Mice Neoplasm Metastasis - physiopathology Neoplasms - etiology Neoplasms - pathology Prognosis
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