Specific Inhibitors of Bacterial Adhesion: Observations From the Study of Gram-Positive Bacteria that Initiate Biofilm Formation on the Tooth Surface

Oral surfaces are bathed in secretory antibodies and other salivary macromolecules that are potential inhibitors of specific microbial adhesion. Indigenous Gram-positive bacteria that colonize teeth, including viridans streptococci and actinomyces, may avoid inhibition of adhesion by host secretory...

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Veröffentlicht in:Advances in dental research 1997-04, Vol.11 (1), p.168-175
Hauptverfasser: Cisar, J.O., Takahashi, Y., Ruhl, S., Donkersloot, J.A., Sandberg, A.L.
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Sprache:eng
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Zusammenfassung:Oral surfaces are bathed in secretory antibodies and other salivary macromolecules that are potential inhibitors of specific microbial adhesion. Indigenous Gram-positive bacteria that colonize teeth, including viridans streptococci and actinomyces, may avoid inhibition of adhesion by host secretory molecules through various strategies that involve the structural design and binding properties of bacterial adhesins and receptors. Further studies to define the interactions of these molecules within the host environment may suggest novel approaches for the control of oral biofilm formation.
ISSN:0895-9374
1544-0737
DOI:10.1177/08959374970110010801