Immunosuppressive activity of a microbial product

Microbial products have amazing diversity and complexity in their chemical structures as well as in their biological activities. The successful discovery and development of FK506 (Tacrolimus) adds a new example showing that microbial products are agents with potential therapeutic benefits. In 1984,...

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Veröffentlicht in:	Folia Pharmacologica Japonica 1997, Vol.110(supplement), pp.69-74
Hauptverfasser:	Hatanaka, Hiroshi, Shimomura, Kyoichi
Format:	Artikel
Sprache:	jpn
Schlagworte:	Animals Autoimmune Diseases - drug therapy Clinical Trials as Topic Cytokines - metabolism Disease Models, Animal Drug Evaluation, Preclinical FK506 Graft Rejection - drug therapy Graft Survival - drug effects Humans Immunosuppressant Immunosuppressive Agents - pharmacology Microbial product MLR T-Lymphocytes - immunology Tacrolimus - pharmacology Transplantation
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