X-Chromosome Inactivation in Monozygotic Twins with Systemic Lupus Erythematosus

The hypothesis that a low concordance rate in monozygotic (MZ) twins with systemic lupus erythematosus (SLE) may be accounted for by differences in X-chromosome inactivation was examined. Five MZ twin pairs, four discordant and one concordant, were recruited, zygosity confirmed by DNA fingerprinting...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Autoimmunity (Chur, Switzerland) Switzerland), 1997-01, Vol.26 (2), p.85-93
Hauptverfasser:	Huang, Qirong, Parfitt, Annette, Grennan, David M., Manolios, Nicholas
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antibodies, Antinuclear - analysis Biological and medical sciences Cheek Diseases in Twins - genetics DNA - analysis DNA Fingerprinting DNA-Cytosine Methylases Dosage Compensation, Genetic Electrophoresis, Agar Gel Electrophoresis, Polyacrylamide Gel Female Genetic Linkage Genetics Humans Lupus Erythematosus, Systemic - genetics Male Medical sciences Microsatellite Repeats - genetics Middle Aged Minisatellite Repeats - genetics Monozygotic Twins Polymerase Chain Reaction Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Systemic lupus erythematosus Twins, Monozygotic - genetics X Chromosome - genetics X Chromosome - physiology X-chromosome inactivation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!