Reduced red-cell folate in mania
Forty-five hospitalised patients with DSM-III-R diagnosis of mania, were found to have a mean red-cell folate level of 193 nmol/l, as compared to 896 nmol/l in the control group ( P
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| Veröffentlicht in: | Journal of affective disorders 1997-11, Vol.46 (2), p.95-99 |
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| container_title | Journal of affective disorders |
| container_volume | 46 |
| creator | Hasanah, C.I Khan, U.A Musalmah, M Razali, S.M |
| description | Forty-five hospitalised patients with DSM-III-R diagnosis of mania, were found to have a mean red-cell folate level of 193 nmol/l, as compared to 896 nmol/l in the control group (
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| doi_str_mv | 10.1016/S0165-0327(97)00096-7 |
| format | Article |
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P<0.00001). Assessment of serum folate in both groups showed no significant difference in the levels. Furthermore the manic patients and the controls were matched by the socio-economic status. This indicated that the reduced red-cell folate in mania is associated with the illness and not due to reduced absorption or dietary deficiency of folate. Considering previous studies that showed reduced red-cell folate in depression, our findings suggest that reduced red-cell folate occurred in both phases of bipolar disorders.</description><identifier>ISSN: 0165-0327</identifier><identifier>EISSN: 1573-2517</identifier><identifier>DOI: 10.1016/S0165-0327(97)00096-7</identifier><identifier>PMID: 9479613</identifier><identifier>CODEN: JADID7</identifier><language>eng</language><publisher>Amsterdam: Elsevier B.V</publisher><subject>Adult ; Adult and adolescent clinical studies ; Biological and medical sciences ; Bipolar Disorder - blood ; Bipolar Disorder - diagnosis ; Erythrocytes - chemistry ; Female ; Folic Acid - analysis ; Folic Acid - blood ; Folic Acid Deficiency - blood ; Folic Acid Deficiency - diagnosis ; Hospitalization ; Humans ; Male ; Mania ; Medical sciences ; Mood disorders ; Psychiatric Status Rating Scales ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Red-cell folate ; Serum folate ; Socioeconomic Factors</subject><ispartof>Journal of affective disorders, 1997-11, Vol.46 (2), p.95-99</ispartof><rights>1997 Elsevier Science B.V.</rights><rights>1998 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c389t-e5a0a19789d6dd8515636e199923bb584e3f74891da62746aa6eb37fea631d393</citedby><cites>FETCH-LOGICAL-c389t-e5a0a19789d6dd8515636e199923bb584e3f74891da62746aa6eb37fea631d393</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0165-0327(97)00096-7$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2129331$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9479613$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hasanah, C.I</creatorcontrib><creatorcontrib>Khan, U.A</creatorcontrib><creatorcontrib>Musalmah, M</creatorcontrib><creatorcontrib>Razali, S.M</creatorcontrib><title>Reduced red-cell folate in mania</title><title>Journal of affective disorders</title><addtitle>J Affect Disord</addtitle><description>Forty-five hospitalised patients with DSM-III-R diagnosis of mania, were found to have a mean red-cell folate level of 193 nmol/l, as compared to 896 nmol/l in the control group (
P<0.00001). Assessment of serum folate in both groups showed no significant difference in the levels. Furthermore the manic patients and the controls were matched by the socio-economic status. This indicated that the reduced red-cell folate in mania is associated with the illness and not due to reduced absorption or dietary deficiency of folate. Considering previous studies that showed reduced red-cell folate in depression, our findings suggest that reduced red-cell folate occurred in both phases of bipolar disorders.</description><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Biological and medical sciences</subject><subject>Bipolar Disorder - blood</subject><subject>Bipolar Disorder - diagnosis</subject><subject>Erythrocytes - chemistry</subject><subject>Female</subject><subject>Folic Acid - analysis</subject><subject>Folic Acid - blood</subject><subject>Folic Acid Deficiency - blood</subject><subject>Folic Acid Deficiency - diagnosis</subject><subject>Hospitalization</subject><subject>Humans</subject><subject>Male</subject><subject>Mania</subject><subject>Medical sciences</subject><subject>Mood disorders</subject><subject>Psychiatric Status Rating Scales</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Red-cell folate</subject><subject>Serum folate</subject><subject>Socioeconomic Factors</subject><issn>0165-0327</issn><issn>1573-2517</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtLxDAQgIMo67r6ExZ6ENFDNWmapHMSWXzBguDjHNJmCpE-NGkF_73Z3bJXLzOH-eb1EbJk9JpRJm_eYhAp5Zm6BHVFKQWZqgMyZ0LxNBNMHZL5HjkmJyF8RkiCojMyg1yBZHxOkle0Y4U28WjTCpsmqfvGDJi4LmlN58wpOapNE_Bsygvy8XD_vnpK1y-Pz6u7dVrxAoYUhaGGgSrASmsLwYTkEhkAZLwsRZEjr1VeALNGZiqXxkgsuarRSM4sB74gF7u5X77_HjEMunVhc5DpsB-DViBkHmdGUOzAyvcheKz1l3et8b-aUb0xo7dm9OZtDUpvzWgV-5bTgrFs0e67JhWxfj7VTahMU3vTVS7ssYxlwDmL2O0Owyjjx6HXoXLYRYXOYzVo27t_DvkDRw18nw</recordid><startdate>19971101</startdate><enddate>19971101</enddate><creator>Hasanah, C.I</creator><creator>Khan, U.A</creator><creator>Musalmah, M</creator><creator>Razali, S.M</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19971101</creationdate><title>Reduced red-cell folate in mania</title><author>Hasanah, C.I ; Khan, U.A ; Musalmah, M ; Razali, S.M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c389t-e5a0a19789d6dd8515636e199923bb584e3f74891da62746aa6eb37fea631d393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Adult</topic><topic>Adult and adolescent clinical studies</topic><topic>Biological and medical sciences</topic><topic>Bipolar Disorder - blood</topic><topic>Bipolar Disorder - diagnosis</topic><topic>Erythrocytes - chemistry</topic><topic>Female</topic><topic>Folic Acid - analysis</topic><topic>Folic Acid - blood</topic><topic>Folic Acid Deficiency - blood</topic><topic>Folic Acid Deficiency - diagnosis</topic><topic>Hospitalization</topic><topic>Humans</topic><topic>Male</topic><topic>Mania</topic><topic>Medical sciences</topic><topic>Mood disorders</topic><topic>Psychiatric Status Rating Scales</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>Red-cell folate</topic><topic>Serum folate</topic><topic>Socioeconomic Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hasanah, C.I</creatorcontrib><creatorcontrib>Khan, U.A</creatorcontrib><creatorcontrib>Musalmah, M</creatorcontrib><creatorcontrib>Razali, S.M</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of affective disorders</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hasanah, C.I</au><au>Khan, U.A</au><au>Musalmah, M</au><au>Razali, S.M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Reduced red-cell folate in mania</atitle><jtitle>Journal of affective disorders</jtitle><addtitle>J Affect Disord</addtitle><date>1997-11-01</date><risdate>1997</risdate><volume>46</volume><issue>2</issue><spage>95</spage><epage>99</epage><pages>95-99</pages><issn>0165-0327</issn><eissn>1573-2517</eissn><coden>JADID7</coden><abstract>Forty-five hospitalised patients with DSM-III-R diagnosis of mania, were found to have a mean red-cell folate level of 193 nmol/l, as compared to 896 nmol/l in the control group (
P<0.00001). Assessment of serum folate in both groups showed no significant difference in the levels. Furthermore the manic patients and the controls were matched by the socio-economic status. This indicated that the reduced red-cell folate in mania is associated with the illness and not due to reduced absorption or dietary deficiency of folate. Considering previous studies that showed reduced red-cell folate in depression, our findings suggest that reduced red-cell folate occurred in both phases of bipolar disorders.</abstract><cop>Amsterdam</cop><pub>Elsevier B.V</pub><pmid>9479613</pmid><doi>10.1016/S0165-0327(97)00096-7</doi><tpages>5</tpages></addata></record> |
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| ispartof | Journal of affective disorders, 1997-11, Vol.46 (2), p.95-99 |
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| subjects | Adult Adult and adolescent clinical studies Biological and medical sciences Bipolar Disorder - blood Bipolar Disorder - diagnosis Erythrocytes - chemistry Female Folic Acid - analysis Folic Acid - blood Folic Acid Deficiency - blood Folic Acid Deficiency - diagnosis Hospitalization Humans Male Mania Medical sciences Mood disorders Psychiatric Status Rating Scales Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Red-cell folate Serum folate Socioeconomic Factors |
| title | Reduced red-cell folate in mania |
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