Amlodipine lowers blood pressure without increasing sympathetic activity or activating the renin-angiotensin system in patients with essential hypertension

Recent clinical studies suggest that the reflex increase in sympathetic nervous activity accompanying a reduction in blood pressure may contribute to the untoward effects of dihydropyridine calcium antagonists. The aim of this study was to examine whether plasma noradrenaline levels and renin activi...

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Veröffentlicht in:	European journal of clinical pharmacology 1997, Vol.53 (3-4), p.197-201
Hauptverfasser:	SASAGURI, M, MATSUMOTO, N, NODA, K, KOGA, M, KINOSHITA, A, IDEISHI, M, ARAKAWA, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Amlodipine - pharmacology Amlodipine - therapeutic use Antihypertensive agents Biological and medical sciences Blood pressure Blood Pressure - drug effects Calcium Channel Blockers - pharmacology Cardiovascular system Female Humans Hypertension Hypertension - drug therapy Hypertension - physiopathology Male Medical research Medical sciences Middle Aged Norepinephrine - blood Pharmacology. Drug treatments Renin - blood Renin-Angiotensin System - drug effects Sympathetic Nervous System - drug effects
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