The Role of Basally Synthesized Nitric Oxide in Modulating the Renal Vasoconstrictor Action of Angiotensin II

Interactions between nitric oxide (NO) and angiotensin (ANG) II in renal vascular beds were examined in anesthetized dogs. The renal blood flow (RBF) response to an intrarenal arterial injection of ANG II was significantly augmented by intrarenal infusion of the NO synthase inhibitor NG-nitro-L-argi...

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Veröffentlicht in:	Hypertension Research 1997, Vol.20(4), pp.251-256
Hauptverfasser:	Aki, Yasuharu, Tomohiro, Atsufumi, Nishiyama, Akira, Kiyomoto, Kayo, Kimura, Shoji, Abe, Youichi
Format:	Artikel
Sprache:	eng
Schlagworte:	angiotensin II Angiotensin II - antagonists & inhibitors Angiotensin II - physiology Animals Antihypertensive Agents - pharmacology Arginine - pharmacology Dogs Enzyme Inhibitors - pharmacology Female Kidney - blood supply Kidney - drug effects Kidney - physiology Male Muscle Tonus - drug effects Muscle Tonus - physiology Muscle, Smooth, Vascular - drug effects NG-nitro-L-arginine nitric oxide Nitric Oxide - physiology Nitric Oxide Synthase - antagonists & inhibitors Nitroarginine - pharmacology Nitroprusside - pharmacology Phenylephrine - pharmacology Pyridines - pharmacology Renal Artery - drug effects renal blood flow Renal Circulation - drug effects sodium nitroprusside Tetrazoles - pharmacology Vasoconstriction - drug effects Vasoconstriction - physiology Vasoconstrictor Agents - pharmacology
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