Anoxia inhibits guanosine salvage in cardiac myocytes

The adult heart depends largely on salvage synthesis to supply its 5'-nucleotide needs. Previous work from this laboratory established that guanosine is metabolized into guanine 5'-nucleotides in heart cells, but that salvage rates are very slow as compared to adenosine. The author hypothe...

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Veröffentlicht in:	Basic research in cardiology 1997-12, Vol.92 (6), p.359-367
1. Verfasser:	Geisbuhler, T P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Hypoxia - physiology Cells, Cultured Guanine Nucleotides - metabolism Guanosine - biosynthesis Guanosine - metabolism Myocardium - metabolism Myocardium - pathology Rats
Online-Zugang:	Volltext
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