Thermodynamic and spectral properties of DNA miniduplexes with the terminal G x A mispairs and 3' or 5' dangling bases

The tetradeoxyribonucleotide pAGCG in 1 M NaCl forms duplexes with terminal non-canonical pA x G pairs with stability significantly exceeding that for the duplex (pAGCT)2 and lower than that for the duplex (pCGCG)2. The deoxyriboduplex (pAGCG)2 is considerably stabilized by 3'-Y and slightly by...

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Veröffentlicht in:	FEBS letters 1997-12, Vol.420 (2-3), p.134-138
Hauptverfasser:	Lokhov, S G, Pyshnyi, D V
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Composition - genetics Circular Dichroism DNA - chemistry Nucleic Acid Conformation Nucleic Acid Denaturation Oligodeoxyribonucleotides - chemical synthesis Oligodeoxyribonucleotides - chemistry Spectrophotometry Thermodynamics
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